tubulin

简明释义

英[ˈtjuːbjʊlɪn]美[ˈtʊbjəlɪn;ˈtjʊbjəlɪn]

n. [生化] 微管蛋白

英英释义

单词用法

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例句

1.Results 5f decreased the Absorption values of the reaction system. and markedly inhibited not only tubulin polymerization but also tubulin depolymerization.

结果5f能抑制反应体系吸光值升高，提示它对微管蛋白聚合具有抑制作用并能抑制其解聚。

2.We extracted rabbit brain tubulin, and then detected by turbidimetric credit made the active ingredient of mahonia the impact of polymerization - depolymerization of tubulin.

提取兔脑微管蛋白采用比浊发检测功劳木活性成分对微管蛋白聚合-解聚的影响。

3.It possesses a unique mechanism of action as promoters of tubulin aseembly and inhibitors of microtubule disassembly.

它的作用机理独特，通过诱导和促进微管蛋白聚合形成稳定结构，从而抑制微管解聚。

4.Another reported Chromene derivatives can strongly inhibit tubulin aggregation and play an efficient role against cancer.

另外有报道色烯类衍生物可以强烈的抑制微管蛋白聚合，从而发挥抗癌作用。

5.Rabbit brain in vitro tubulin polymerization-depolymerization showed that jatrorrhizine and berberine can inhibit tubulin polymerization, and jatrorrhizine are stronger than that of berberine.

体外兔脑微管蛋白聚合-解聚分析表明，药根碱和小檗碱均能抑制微管蛋白的聚合，且药根碱作用强于小檗碱。

6.Target compounds 4 and 5 were tested in a tubulin assembly assay, and in an in vitro cytotoxicity assay(KB cell line).

将目标化合物进行了抗肿瘤体外试验和微管聚合试验。

7.Conclusion 5f inhibits tubulin polymerization and depolymerization, and leads to cell cycle arrested, and possibly induces apoptosis.

结论5f能抑制体外微管蛋白聚合，从而可能是影响细胞的细胞周期及诱导凋亡途径之一。

8.Rabbit brain in vitro tubulin polymerization-depolymerization showed that jatrorrhizine and berberine can inhibit tubulin polymerization, and jatrorrhizine are stronger than that of berberine.

体外兔脑微管蛋白聚合-解聚分析表明，药根碱和小檗碱均能抑制微管蛋白的聚合，且药根碱作用强于小檗碱。

9.The binding of drugs to tubulin can inhibit cancer cell proliferation.

药物与微管蛋白结合可以抑制癌细胞增殖。

10.The structure of tubulin is essential for the formation of microtubules.

结构中的微管蛋白对微管的形成至关重要。

11.In neurons, tubulin is involved in the transport of organelles.

在神经元中，微管蛋白参与细胞器的运输。

12.Research shows that alterations in tubulin dynamics can lead to cancer.

研究表明，微管蛋白动态的改变可能导致癌症。

13.During cell division, tubulin plays a critical role in spindle formation.

在细胞分裂过程中，微管蛋白在纺锤体形成中起着关键作用。

作文

Tubulin is a protein that plays a crucial role in the structure and function of cells. It is a key component of microtubules, which are part of the cytoskeleton. The cytoskeleton is essential for maintaining cell shape, enabling cellular movement, and facilitating intracellular transport. Microtubules are dynamic structures made up of tubulin dimers, which means they consist of two subunits: alpha-tubulin and beta-tubulin. These dimers polymerize to form long, hollow tubes that provide structural support to the cell.The importance of tubulin (微管蛋白) cannot be overstated. In addition to providing mechanical support, microtubules serve as tracks for the movement of organelles and vesicles within cells. Motor proteins, such as kinesin and dynein, travel along these microtubules to transport cellular cargo. This process is vital for maintaining cellular functions and responding to changes in the environment.Moreover, tubulin (微管蛋白) is involved in cell division. During mitosis, microtubules form the mitotic spindle, which separates chromosomes into daughter cells. Any disruption in the function of tubulin (微管蛋白) can lead to severe consequences, including cancer. Many chemotherapeutic agents target microtubule dynamics, inhibiting the ability of cancer cells to divide and proliferate.Research on tubulin (微管蛋白) has expanded significantly over the years. Scientists have discovered various post-translational modifications of tubulin (微管蛋白), such as acetylation and detyrosination, which can influence microtubule stability and function. Understanding these modifications provides insights into how cells regulate their internal processes and respond to external stimuli.In summary, tubulin (微管蛋白) is a fundamental protein that is integral to many cellular processes. Its role in forming microtubules highlights its importance in maintaining cell structure, facilitating movement, and ensuring proper cell division. As research continues to uncover the complexities of tubulin (微管蛋白) and its interactions within the cell, it becomes increasingly clear that this protein is not just a building block of the cytoskeleton but also a key player in the intricate dance of life at the cellular level.

微管蛋白是一个在细胞结构和功能中起着关键作用的蛋白质。它是微管的一个关键组成部分，而微管是细胞骨架的一部分。细胞骨架对于维持细胞形状、促进细胞运动以及促进细胞内运输是必不可少的。微管是由微管蛋白二聚体组成的动态结构，这意味着它们由两个亚单位组成：α-微管蛋白和β-微管蛋白。这些二聚体聚合形成长而空心的管道，为细胞提供结构支持。微管蛋白的重要性不言而喻。除了提供机械支持外，微管还作为细胞内器官和囊泡移动的轨道。运动蛋白，如驱动蛋白和动力蛋白，沿着这些微管移动以运输细胞货物。这一过程对于维持细胞功能和应对环境变化至关重要。此外，微管蛋白参与细胞分裂。在有丝分裂期间，微管形成了有丝分裂纺锤体，将染色体分开到子细胞中。任何对微管蛋白功能的干扰都可能导致严重后果，包括癌症。许多化疗药物针对微管动力学，抑制癌细胞分裂和增殖的能力。关于微管蛋白的研究在近年来显著扩大。科学家们发现微管蛋白的各种翻译后修饰，如乙酰化和去酪氨酸化，这可以影响微管的稳定性和功能。理解这些修饰提供了细胞如何调节其内部过程和响应外部刺激的洞察。总之，微管蛋白是一个基本的蛋白质，对于许多细胞过程至关重要。它在形成微管中的作用突显了其在维持细胞结构、促进运动和确保适当细胞分裂中的重要性。随着研究继续揭示微管蛋白及其在细胞内相互作用的复杂性，越来越清楚的是，这种蛋白质不仅是细胞骨架的构建块，而且是细胞层面生命复杂舞蹈中的关键角色。