polyclonal

简明释义

英[ˌpɒlɪˈkləʊn(ə)l]美[ˌpɑliˈklonəl]

adj. 多克隆的；多元性繁殖系的；多细胞系的

英英释义

单词用法

同义词

反义词

例句

1.Then polyclonal antibody of nt was acquired from animal immunization of this production.

用此合成产物进行动物体免疫，获得了NT的多克隆抗体。

2.Objective: To produce rabbit polyclonal antibody of murine PC 1 protein and detect its expression profile in mouse organs.

目的：获得小鼠pc1蛋白的兔多克隆抗体，检测其在小鼠器官中的表达谱。

3.Polyclonal antibodies are produced by immunizing animals with a synthetic DYKDDDDK peptide. Antibodies are purified by protein a and peptide affinity chromatography.

多克隆抗体通过用DYKDDDDK合成肽免疫动物制备。抗体用蛋白a和多肽亲和色谱法纯化。

4.Objective to purify the immunoglobulin from Ricefield eel, and to prepare the rabbit polyclonal antisera.

目的分离纯化黄鳝血清免疫球蛋白，制备其兔抗血清，并检测抗血清的特异性。

5.Polyclonal antibody preparation against the peptides of NDRG family proteins.

抗人ndrg家族寡肽的多克隆抗体制备。

6.The specificity of the purified polyclonal antibody was identified by indirect fluorescence staining and FCM analysis.

间接免疫荧光染色及流式细胞术鉴定多克隆抗体的特异性。

7.Objective To investigate the application value of detection of PGL-I antigen by using PGL-I polyclonal antibody in the diagnosis of leprosy.

目的探讨采用酚糖脂- I (PGL - I)多克隆抗体检测皮肤活检标本中PG L - I抗原对麻风诊断和鉴别诊断的价值。

8.Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding amino acid 710 of human FAK.

多克隆抗体由合成的肽段免疫动物产生，该肽段与人fak的710位氨基酸附近残基对应。

9.An indirect competitive enzyme-linked immunosorbent assay (IC-ELISA) for cypermethrin and cyhalothrin was developed and optimized by using polyclonal antibodies.

利用自制抗体建立并优化了氯氰菊酯和三氟氯氰菊酯的间接竞争ELISA (IC - ELISA)检测方法。

10.Diagnostic tests often utilize polyclonal 多克隆的 antibodies for better sensitivity.

诊断测试通常利用多克隆的抗体以提高灵敏度。

11.In laboratory studies, researchers often use polyclonal 多克隆的 antibodies to detect various proteins.

在实验室研究中，研究人员经常使用多克隆的抗体来检测各种蛋白质。

12.A polyclonal 多克隆的 antibody mixture can provide broader protection than a monoclonal antibody.

与单克隆抗体相比，多克隆的抗体混合物可以提供更广泛的保护。

13.The immune response generated by the body is often a polyclonal 多克隆的 response, involving multiple types of antibodies.

身体产生的免疫反应通常是一个多克隆的反应，涉及多种类型的抗体。

14.The vaccine was designed to stimulate a strong polyclonal 多克隆的 antibody response against the virus.

该疫苗旨在刺激对病毒的强烈多克隆的抗体反应。

作文

In the field of immunology, the term polyclonal refers to a type of immune response that involves multiple types of antibodies. Unlike monoclonal antibodies, which are derived from a single clone of B cells and recognize only one specific antigen, polyclonal antibodies are produced by different B cell lineages. This diversity allows for a broader recognition of various epitopes on an antigen, making polyclonal antibodies particularly useful in research and clinical applications.The production of polyclonal antibodies typically involves the immunization of an animal, such as a rabbit or goat, with a specific antigen. The animal's immune system responds by generating a wide range of antibodies that can bind to different parts of the antigen. After a period of time, blood is collected from the animal, and the serum containing the polyclonal antibodies is extracted. This serum can then be used for various purposes, including diagnostic tests, therapeutic interventions, and research studies.One of the key advantages of using polyclonal antibodies is their ability to recognize multiple epitopes, which can enhance the sensitivity of assays. For instance, in enzyme-linked immunosorbent assays (ELISAs), the presence of polyclonal antibodies can lead to stronger and more reliable signals compared to monoclonal antibodies. This is particularly important in detecting low-abundance proteins or antigens in complex biological samples.However, there are also some limitations associated with polyclonal antibodies. Since they are derived from multiple B cell clones, there can be variability in the quality and specificity of the antibodies produced. This can lead to batch-to-batch differences, which may affect the reproducibility of experiments. Additionally, the use of polyclonal antibodies can sometimes result in cross-reactivity, where the antibodies bind to unintended targets, leading to false-positive results.Despite these challenges, polyclonal antibodies remain an essential tool in many areas of biological research and medicine. They have been widely used in the detection of infectious diseases, cancer biomarkers, and autoimmune disorders. In therapeutic settings, polyclonal antibodies can be administered to patients to help boost their immune response against specific pathogens or cancer cells.In conclusion, understanding the concept of polyclonal antibodies is crucial for anyone working in the life sciences. Their ability to recognize multiple epitopes provides significant advantages in various applications, although researchers must also be aware of the potential drawbacks. As technology advances, the development of more refined and specific polyclonal antibodies will likely continue to enhance their utility in both research and clinical settings. Overall, the role of polyclonal antibodies in immunology highlights the complexity and sophistication of the immune response, showcasing the remarkable ability of the body to defend itself against a diverse array of threats.

在免疫学领域，术语多克隆指的是一种涉及多种抗体的免疫反应。与单克隆抗体不同，单克隆抗体是来源于单一克隆B细胞并且只识别一个特定抗原，而多克隆抗体则是由不同的B细胞谱系产生的。这种多样性使得多克隆抗体能够更广泛地识别抗原上的各种表位，这使得多克隆抗体在研究和临床应用中尤为有用。多克隆抗体的生产通常涉及对动物（如兔子或山羊）进行特定抗原的免疫接种。动物的免疫系统会产生多种抗体，以结合抗原的不同部分。经过一段时间后，从动物体内采集血液，提取含有多克隆抗体的血清。然后，这种血清可用于各种用途，包括诊断测试、治疗干预和研究研究。使用多克隆抗体的一个主要优点是它们能够识别多个表位，这可以增强检测的灵敏度。例如，在酶联免疫吸附试验（ELISA）中，使用多克隆抗体可能会导致比单克隆抗体更强和更可靠的信号。这在检测复杂生物样本中低丰度蛋白或抗原时尤其重要。然而，使用多克隆抗体也存在一些局限性。由于它们源自多个B细胞克隆，因此所产生的抗体的质量和特异性可能会有所不同。这可能导致批次之间的差异，从而影响实验的重复性。此外，使用多克隆抗体有时会导致交叉反应，即抗体结合到非目标物质上，从而导致假阳性结果。尽管存在这些挑战，多克隆抗体仍然是生物研究和医学中不可或缺的工具。它们被广泛用于检测传染病、癌症生物标志物和自身免疫性疾病。在治疗环境中，可以将多克隆抗体施用于患者，以帮助增强其针对特定病原体或癌细胞的免疫反应。总之，理解多克隆抗体的概念对于任何从事生命科学工作的人来说都是至关重要的。它们能够识别多个表位，在各种应用中提供显著优势，尽管研究人员还必须意识到潜在的缺陷。随着技术的进步，更加精细和特异的多克隆抗体的发展可能会继续增强其在研究和临床环境中的实用性。总体而言，多克隆抗体在免疫学中的作用突显了免疫反应的复杂性和精密性，展示了身体抵御各种威胁的卓越能力。