coagulase

简明释义

英[kəʊˈæɡjʊleɪz]美[koʊˈæɡjəˌleɪs]

n. [生化] 凝固酶；凝固酵素

英英释义

单词用法

同义词

反义词

例句

1.About 89.5% of S. aureus isolate were identified as methicillin-resistant Staphylococcus, 83.3% of coagulase negative Staphylococcus isolates were methicillin-resistant.

金黄色葡萄球菌和凝固酶阴性葡萄球菌中耐甲氧西林株分别占89.5%和83.3%。

2.The strains were tested with catalase and coagulase tests, biochemical experiments were used to identify the strain.

对分离的菌株，用过氧化氢酶和血浆凝固酶试验后，用生化实验对菌株进行鉴定。

3.Results Coagulase negative Staphylococci (CNS) accounted for more than 50% every year.

结果凝固酶阴性葡萄球菌（CNS）检出构成比历年居于5 0 %以上。

4.The positive rate of escherichia coli was the highest followed by coagulase negative staphylococci, klebsiella pneumoniae and blue verditer pseudomonas.

阳性率最高的是肠埃希菌，其次是凝固酶阴性葡萄球菌、克雷伯菌、铜绿假单胞菌。

5.Coagulase negative Staphylococcus (CNS) (15.7% of the isolates) was the most frequently isolated pathogen, followed by Staphylococcus aureus, Escherichia coli, Pseudomonas SPP and Acinetobacter SPP.

最常见的病原菌是凝固酶阴性葡萄球菌(CNS)，占15.7%，其次是金黄色葡萄球菌、大肠埃希菌、假单胞菌属、不动杆菌属。

6.To study the influence of slide coagulase test on determining the staphylococcus aureus (sa) with GPI assay.

目的了解玻片法凝固酶试验在GPI卡鉴定金黄色葡萄球菌(SA)中的影响。

7.Objective: To evaluate the clinical significance of coagulase negative staphylococci (CNS) in blood culture.

目的：评价血培养中凝固酶阴性葡萄球菌(CNS)阳性的临床意义。

8.The presence of coagulase indicates that the bacteria can clot blood, which is a key factor in identifying pathogenic strains.

存在凝固酶表明细菌能够凝血，这是识别致病菌株的一个关键因素。

9.The coagulase enzyme plays a crucial role in the pathogenesis of certain bacterial infections.

凝固酶酶在某些细菌感染的发病机制中起着至关重要的作用。

10.Some strains of Staphylococcus produce coagulase, allowing them to evade the immune system.

一些葡萄球菌株产生凝固酶，使它们能够逃避免疫系统。

11.A positive coagulase test can confirm the presence of virulent strains of bacteria in clinical samples.

阳性凝固酶测试可以确认临床样本中存在毒力菌株。

12.In laboratory tests, coagulase is used to differentiate Staphylococcus aureus from other staphylococci.

在实验室测试中，凝固酶用于区分金黄色葡萄球菌与其他葡萄球菌。

作文

Coagulase is an important enzyme that plays a significant role in the medical field, particularly in microbiology and immunology. It is primarily produced by certain strains of bacteria, most notably Staphylococcus aureus. The function of coagulase (凝固酶) is to convert fibrinogen, a soluble plasma protein, into insoluble fibrin strands, leading to the coagulation of blood. This process is crucial for the formation of clots, which can help prevent excessive bleeding in wounds. However, the presence of coagulase (凝固酶) can also be indicative of pathogenic bacteria, as many virulent strains produce this enzyme to evade the host's immune response.In clinical settings, the detection of coagulase (凝固酶) is often used as a diagnostic tool to identify Staphylococcus aureus infections. When a sample from a patient is incubated with plasma, the presence of coagulase (凝固酶) will result in clot formation, confirming the presence of this particular bacterium. This is especially important because Staphylococcus aureus is associated with a variety of serious infections, including skin infections, pneumonia, and bloodstream infections.The role of coagulase (凝固酶) in the pathogenesis of Staphylococcus aureus cannot be overstated. By promoting clot formation, these bacteria can create a protective barrier around themselves, shielding them from phagocytosis by immune cells. This allows the bacteria to persist in the host and contribute to ongoing infection and inflammation. Additionally, coagulase (凝固酶) production is often linked to other virulence factors that enhance the bacterium's ability to cause disease.Research into coagulase (凝固酶) has also led to advancements in our understanding of bacterial resistance mechanisms. For instance, some strains of Staphylococcus aureus have developed resistance to methicillin, leading to the emergence of Methicillin-resistant Staphylococcus aureus (MRSA). These resistant strains continue to pose significant challenges in healthcare settings, making early detection and appropriate treatment crucial.In summary, coagulase (凝固酶) is more than just an enzyme; it is a key player in the interaction between pathogenic bacteria and the host's immune system. Its ability to induce clot formation has both beneficial and detrimental effects, depending on the context. Understanding the role of coagulase (凝固酶) in bacterial infections can help inform clinical practices and lead to better management strategies for infections caused by Staphylococcus aureus. Continued research into this enzyme and its implications in disease will undoubtedly contribute to improved public health outcomes and the development of more effective therapeutic interventions.

凝固酶是一个重要的酶，在医学领域，尤其是在微生物学和免疫学中发挥着重要作用。它主要由某些细菌株产生，最著名的是金黄色葡萄球菌。coagulase（凝固酶）的功能是将可溶性血浆蛋白纤维蛋白原转化为不溶性的纤维蛋白链，从而导致血液的凝固。这个过程对于形成血块至关重要，可以帮助防止伤口过度出血。然而，coagulase（凝固酶）的存在也可能表明致病细菌的存在，因为许多致病菌株会产生这种酶以逃避宿主的免疫反应。在临床环境中，coagulase（凝固酶）的检测通常作为诊断工具，用于识别金黄色葡萄球菌感染。当患者样本与血浆一起培养时，coagulase（凝固酶）的存在将导致凝块形成，确认这种特定细菌的存在。这一点尤其重要，因为金黄色葡萄球菌与多种严重感染相关，包括皮肤感染、肺炎和血流感染。coagulase（凝固酶）在金黄色葡萄球菌致病机制中的作用不容小觑。通过促进凝块的形成，这些细菌可以在周围形成保护屏障，保护自己免受免疫细胞的吞噬。这使得细菌能够在宿主体内持续存在，并促成持续的感染和炎症。此外，coagulase（凝固酶）产生通常与其他增强细菌致病能力的毒力因子相关联。对coagulase（凝固酶）的研究也推动了我们对细菌耐药机制的理解。例如，一些金黄色葡萄球菌株已发展出对甲氧西林的耐药性，导致了耐甲氧西林金黄色葡萄球菌（MRSA）的出现。这些耐药菌株在医疗环境中继续构成重大挑战，使得早期检测和适当治疗至关重要。总之，coagulase（凝固酶）不仅仅是一个酶；它是致病细菌与宿主免疫系统相互作用中的关键角色。它诱导凝块形成的能力在不同的情况下具有有益和有害的影响。了解coagulase（凝固酶）在细菌感染中的作用可以帮助指导临床实践，并导致更好的金黄色葡萄球菌感染管理策略。对这一酶及其在疾病中的影响的持续研究无疑将有助于改善公共卫生结果和开发更有效的治疗干预措施。