bacillus calmette gurin

简明释义

结核预防注射液

英英释义

例句

1.Doctors recommend the bacillus calmette gurin 卡介苗 for infants in high-risk areas.

医生建议高风险地区的婴儿接种bacillus calmette gurin 卡介苗。

2.The bacillus calmette gurin 卡介苗 vaccine is widely used to prevent tuberculosis.

广泛使用的bacillus calmette gurin 卡介苗 疫苗用于预防结核病。

3.Many countries have implemented universal vaccination with bacillus calmette gurin 卡介苗 in their health programs.

许多国家在其健康计划中实施了对bacillus calmette gurin 卡介苗 的普遍接种。

4.The efficacy of bacillus calmette gurin 卡介苗 is particularly important in developing nations.

在发展中国家，bacillus calmette gurin 卡介苗 的有效性尤为重要。

5.Research shows that bacillus calmette gurin 卡介苗 can have protective effects beyond tuberculosis.

研究表明，bacillus calmette gurin 卡介苗 除了对结核病有保护作用外，还可能有其他保护效果。

作文

The term bacillus calmette gurin refers to a strain of the bacterium Mycobacterium bovis that has been attenuated for use in vaccines. This particular strain was developed by Albert Calmette and Camille Guérin in the early 20th century, specifically for the purpose of immunizing against tuberculosis (TB). As one of the first vaccines developed for a bacterial infection, the bacillus calmette gurin vaccine, commonly known as BCG vaccine, has played a crucial role in public health, particularly in countries where tuberculosis is endemic. The development of the bacillus calmette gurin vaccine marks a significant milestone in medical history. Prior to its introduction, tuberculosis was a leading cause of death worldwide, with millions succumbing to this infectious disease each year. The BCG vaccine was introduced in the 1920s and has since been administered to billions of people around the globe. Its effectiveness varies by region, but it is widely recognized for its ability to prevent severe forms of TB, such as TB meningitis and disseminated TB in children.The mechanism through which the bacillus calmette gurin vaccine operates is fascinating. When the vaccine is administered, it stimulates the immune system to recognize and fight off Mycobacterium tuberculosis, the bacterium responsible for the disease. This process involves the activation of T-cells and other immune responses, which create a memory that allows the body to respond more effectively if exposed to the actual pathogen in the future. Despite its benefits, the bacillus calmette gurin vaccine is not without limitations. For instance, it does not provide complete protection against tuberculosis, and its efficacy can vary based on geographic location and the age of the recipient. Additionally, some individuals may experience adverse reactions to the vaccine, although these are generally mild and temporary. In recent years, the global burden of tuberculosis has prompted renewed interest in improving the bacillus calmette gurin vaccine and developing new vaccines altogether. Researchers are exploring various strategies to enhance the immune response elicited by BCG and to create more effective alternatives. This includes studying different formulations, delivery methods, and adjuvants that could boost the vaccine's performance. Moreover, the ongoing challenge of antibiotic resistance has underscored the importance of vaccination as a primary prevention strategy. With the rise of multidrug-resistant strains of tuberculosis, the need for effective vaccines like the bacillus calmette gurin becomes even more critical. Public health initiatives continue to advocate for the use of BCG in high-risk populations, emphasizing its role in reducing the incidence of severe TB cases. In conclusion, the bacillus calmette gurin vaccine remains a vital tool in the fight against tuberculosis. Its historical significance, coupled with its ongoing relevance in contemporary medicine, showcases the importance of vaccines in controlling infectious diseases. As research progresses, there is hope for improved vaccines that can further reduce the burden of tuberculosis and protect future generations from this devastating disease.

术语bacillus calmette gurin指的是一种减毒的牛分枝杆菌（Mycobacterium bovis）菌株，专门用于疫苗接种。这种特定的菌株是由阿尔贝特·卡尔梅特（Albert Calmette）和卡米尔·居里安（Camille Guérin）在20世纪初开发的，目的是为了预防结核病（TB）。作为首个针对细菌感染开发的疫苗之一，bacillus calmette gurin疫苗，通常称为BCG疫苗，在公共卫生中发挥了重要作用，特别是在结核病流行的国家。bacillus calmette gurin疫苗的开发标志着医学历史上的一个重要里程碑。在其引入之前，结核病是全球主要的死亡原因之一，每年有数百万人死于这一传染病。BCG疫苗于1920年代推出，自此已在全球数十亿人中接种。其有效性因地区而异，但普遍被认为可以预防严重形式的结核病，如儿童结核性脑膜炎和播散性结核。bacillus calmette gurin疫苗的作用机制非常有趣。当接种疫苗时，它刺激免疫系统识别并抵御结核分枝杆菌（Mycobacterium tuberculosis），该细菌是导致结核病的病原体。这个过程涉及T细胞和其他免疫反应的激活，形成一种记忆，允许身体在未来面对实际病原体时更有效地作出反应。尽管有其好处，bacillus calmette gurin疫苗并非没有局限性。例如，它并不能提供对结核病的完全保护，其有效性可能因地理位置和受种者的年龄而异。此外，一些个体可能会对疫苗产生不良反应，尽管这些反应通常是轻微和暂时的。近年来，全球结核病负担的加重促使人们重新关注改善bacillus calmette gurin疫苗和开发新疫苗的工作。研究人员正在探索多种策略，以增强BCG引发的免疫反应，并创造更有效的替代品。这包括研究不同的配方、给药方法和能够增强疫苗性能的佐剂。此外，抗生素耐药性问题的持续挑战强调了疫苗接种作为主要预防策略的重要性。随着多重耐药性结核菌株的增加，对有效疫苗如bacillus calmette gurin的需求变得更加紧迫。公共卫生倡导继续提倡在高风险人群中使用BCG，强调其在减少严重结核病例发生中的作用。总之，bacillus calmette gurin疫苗仍然是对抗结核病的重要工具。它的历史意义，加上在当代医学中的持续相关性，展示了疫苗在控制传染病中的重要性。随着研究的进展，人们对改进疫苗的希望越来越大，这将进一步减少结核病的负担，保护未来几代人免受这一毁灭性疾病的侵害。