immunogenicity

简明释义

英[ˌɪmjunəˈdʒɛnɪsɪti]美[ˌɪmjunəˈdʒɛnɪsɪti]

n. [免疫] 免疫原性；致免疫性；致免疫力

英英释义

单词用法

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例句

1.Newborn larvae antigens of Trichinella spiralis have better immunogenicity, which can induce an obvious immune protection against T. spiralis.

旋毛虫新生幼虫抗原具有很好的免疫原性，有明显的抗旋毛虫保护性免疫作用。

2.As a small polypeptide, without cytotoxicity and immunogenicity, TAT PTD protein don't affect the function of the fused proteins.

而且，TATPTD的分子量小，无细胞毒性，免疫原性极低，不影响融合的蛋白功能。

3.With the time going the immunogenicity will show the descent tendency.

免疫原性会随着时间的延长有下降趋势。

4."It's up to the international standard for safety and immunogenicity factors," Zhao said Monday at the experts certification meeting.

“这是由国际安全和免疫原性因素标准决定的，”赵凯在周一举行的专家认证会议上说。

5.The key of antibody-mediated immunological therapy is strong specificity of target antigen, low immunogenicity, high affinity of antibody and so on.

而抗体介导的免疫治疗的关键是靶抗原的特异性强，抗体的免疫原性低及亲和力高等。

6.But most of the antigen was the kind of self-antigen with the defects of poor-immunogenicity and easily-caused immunotolerance.

但这些抗原多属自身抗原，普遍存在免疫原性低，易引起免疫耐受等缺陷。

7.OBJECTIVE: To investigate the effects of liquid nitrogen cryopreservation on osteoblast immunogenicity.

目的：探讨液氮冷冻对成骨细胞免疫原性的影响。

8.The vaccine's immunogenicity was tested in clinical trials to ensure it would elicit a strong immune response.

该疫苗的免疫原性在临床试验中进行了测试，以确保它能够引发强烈的免疫反应。

9.The immunogenicity of a new therapeutic protein is crucial for its success in treating diseases.

新治疗蛋白的免疫原性对于其在治疗疾病中的成功至关重要。

10.The team evaluated the immunogenicity of the modified virus to assess its potential as a vaccine candidate.

团队评估了改造病毒的免疫原性以评估其作为疫苗候选者的潜力。

11.Researchers are studying the immunogenicity of different adjuvants to enhance vaccine effectiveness.

研究人员正在研究不同佐剂的免疫原性以增强疫苗的有效性。

12.High immunogenicity can lead to unwanted side effects, making it important to balance efficacy and safety.

高免疫原性可能导致不良副作用，因此在有效性和安全性之间保持平衡非常重要。

作文

Immunogenicity is a critical concept in the fields of immunology and vaccine development. It refers to the ability of a substance, such as a vaccine or an antigen, to provoke an immune response in the body. This response is essential for the body to recognize and fight off pathogens like viruses and bacteria. Understanding the factors that influence immunogenicity (免疫原性) is vital for researchers and healthcare professionals alike, as it can determine the effectiveness of vaccines and therapeutic agents.One of the primary determinants of immunogenicity (免疫原性) is the nature of the antigen itself. Antigens are typically proteins or polysaccharides that are recognized by the immune system. The complexity and structure of these molecules can significantly influence their ability to elicit an immune response. For instance, larger and more complex antigens tend to be more immunogenic than smaller, simpler ones. This is because larger antigens can present multiple epitopes, or parts of the antigen that are recognized by immune cells, thus enhancing the likelihood of an immune response.Another important factor affecting immunogenicity (免疫原性) is the route of administration. Different methods of delivering a vaccine can lead to varying levels of immune response. For example, intramuscular injections may stimulate a stronger response compared to oral vaccines. This is largely due to the differences in how the immune system is activated based on the route of exposure. Additionally, the presence of adjuvants, substances that enhance the body's immune response to an antigen, can also play a significant role in increasing the immunogenicity (免疫原性) of a vaccine.The timing and dosage of vaccine administration are also crucial elements that impact immunogenicity (免疫原性). Administering the correct dose at the right intervals can help ensure that the immune system is adequately primed to respond to subsequent exposures. For instance, many vaccines require a series of doses to build up sufficient immunity, as seen with the measles, mumps, and rubella (MMR) vaccine.Moreover, individual variability among patients can affect immunogenicity (免疫原性). Factors such as age, genetic background, and overall health can influence how well a person's immune system responds to a vaccine. For example, elderly individuals often have a weaker immune response compared to younger adults, which can result in lower immunogenicity (免疫原性) for certain vaccines. This highlights the importance of tailoring vaccination strategies to different populations to optimize immune responses.In conclusion, immunogenicity (免疫原性) is a fundamental aspect of vaccine development and immunology that encompasses various factors, including the nature of the antigen, the route of administration, timing, dosage, and individual patient characteristics. By advancing our understanding of these factors, researchers can develop more effective vaccines that provide better protection against infectious diseases. As we continue to face global health challenges, enhancing immunogenicity (免疫原性) will remain a priority in the pursuit of effective immunization strategies.