Acute Oral Toxicity

简明释义

口摄取半致死量

英英释义

例句

1.To ensure safety, manufacturers must assess Acute Oral Toxicity 急性口服毒性 during the product development phase.

为了确保安全，制造商必须在产品开发阶段评估急性口服毒性。

2.The results indicated a high level of Acute Oral Toxicity 急性口服毒性 in the tested compound.

结果表明，所测试化合物具有较高的急性口服毒性。

3.The study aimed to evaluate the Acute Oral Toxicity 急性口服毒性 of the new pesticide on laboratory animals.

该研究旨在评估新农药对实验动物的急性口服毒性。

4.The laboratory conducted a series of tests to determine the Acute Oral Toxicity 急性口服毒性 of various household cleaners.

实验室进行了系列测试，以确定各种家用清洁剂的急性口服毒性。

5.Regulatory agencies often require testing for Acute Oral Toxicity 急性口服毒性 before approving new chemicals.

监管机构通常要求在批准新化学物质之前进行急性口服毒性测试。

作文

Understanding the concept of Acute Oral Toxicity is crucial for both medical professionals and researchers in toxicology. This term refers to the harmful effects that can occur when a substance is ingested in a single dose or multiple doses within a short period, typically less than 24 hours. The evaluation of Acute Oral Toxicity is essential for assessing the safety of chemicals, pharmaceuticals, and various consumer products. It helps in determining the potential risks associated with exposure to these substances. In toxicology, acute toxicity tests are conducted to establish a dose-response relationship, which indicates how different amounts of a substance can lead to varying degrees of toxicity. These tests often involve administering a specific quantity of a substance to laboratory animals, such as rats or mice, and observing the effects over a defined period. The data collected from these studies provide valuable insights into the lethal dose (LD50), which is the amount of substance required to kill 50% of the test population. Understanding Acute Oral Toxicity is critical in the process of drug development as well. Before any new medication can be approved for human use, it must undergo rigorous testing to ensure that it does not pose a significant risk when ingested. Regulatory agencies, such as the U.S. Food and Drug Administration (FDA), require comprehensive toxicity data to make informed decisions regarding the safety of new drugs. Moreover, awareness of Acute Oral Toxicity extends beyond the laboratory. It is vital for public health and safety, particularly in industries that handle hazardous materials. For example, workers in chemical manufacturing or agriculture must be trained to recognize the signs of acute poisoning and understand the proper safety protocols to follow in case of exposure. Additionally, consumers need to be informed about the potential risks associated with household products, such as cleaning agents or pesticides, which may contain toxic substances. Education plays a significant role in promoting understanding of Acute Oral Toxicity. Schools and universities should incorporate toxicology into their curricula to equip future generations with the knowledge necessary to navigate issues related to chemical safety. Furthermore, public awareness campaigns can help inform individuals about the dangers of ingesting unknown substances, whether they are medications, recreational drugs, or even certain plants and mushrooms. In conclusion, the concept of Acute Oral Toxicity encompasses a wide range of implications for health, safety, and regulatory practices. By comprehensively understanding this term, we can better protect ourselves and others from the potentially harmful effects of toxic substances. Ongoing research and education in this field are essential for advancing our knowledge and ensuring the safety of the products we use every day. As we continue to explore the complexities of toxicity, it is imperative that we remain vigilant and informed about the substances we encounter in our lives.

理解急性口服毒性的概念对于医疗专业人员和毒理学研究人员至关重要。该术语指的是在短时间内（通常少于24小时）摄入单剂量或多剂量物质时可能发生的有害影响。评估急性口服毒性对于评估化学品、药物和各种消费品的安全性至关重要。它有助于确定与这些物质接触相关的潜在风险。在毒理学中，急性毒性测试用于建立剂量反应关系，即不同数量的物质如何导致不同程度的毒性。这些测试通常涉及将特定数量的物质施用给实验动物，如大鼠或小鼠，并观察在规定时间内的影响。从这些研究中收集的数据提供了关于致死剂量（LD50）的宝贵见解，即使50%的实验群体死亡所需的物质数量。理解急性口服毒性在药物开发过程中至关重要。在任何新药物获得人类使用批准之前，必须经过严格测试，以确保其在摄入时不会构成重大风险。监管机构，如美国食品和药物管理局（FDA），要求提供全面的毒性数据，以便就新药的安全性做出明智的决定。此外，对急性口服毒性的认识超越了实验室。它对公共健康和安全至关重要，特别是在处理危险材料的行业。例如，化工制造或农业中的工人必须接受培训，以识别急性中毒的迹象，并了解在接触时应遵循的适当安全协议。此外，消费者需要了解与家用产品（如清洁剂或杀虫剂）相关的潜在风险，这些产品可能含有有毒物质。教育在促进对急性口服毒性的理解中发挥着重要作用。学校和大学应将毒理学纳入其课程，以使未来的几代人具备应对与化学安全相关问题所需的知识。此外，公共意识活动可以帮助告知个人有关摄入未知物质的危险，无论它们是药物、娱乐性药物，还是某些植物和蘑菇。总之，急性口服毒性的概念涵盖了健康、安全和监管实践的广泛影响。通过全面理解这个术语，我们可以更好地保护自己和他人免受有毒物质的潜在有害影响。该领域的持续研究和教育对于提高我们的知识和确保我们每天使用的产品的安全性至关重要。随着我们继续探索毒性的复杂性，保持警惕并了解我们生活中遇到的物质是至关重要的。