meperidine

简明释义

英[meˈperɪdiːn]美[məˈperəˌdɪn]

n. 哌替啶（麻醉镇静剂）

英英释义

单词用法

同义词

反义词

例句

1.Demerol: a trademark used for a medicinal preparation of meperidine.

德美罗：用于镇痛药哌替啶的一种商标。

2.Using meperidine abusers as subjects for this study, we detected in hair meperidine and its metabolites normeperidine, N - OCH3 - meperidine and N - AC meperidine.

以度冷丁滥用者为研究对象，在度冷丁滥用者毛发中检出度冷丁及代谢物去甲度冷丁、N一羟甲基度冷丁和N-乙酰度冷丁。

3.Our study aims were to investigate analgesic efficacy and to quantify the plasma concentrations of meperidine and ropivacaine after IP administration.

我们的研究目的是调查腹膜内给予呱替啶和罗呱卡因的镇痛效果并检测血浆浓度。

4.Objective To observe the effect of diaphragm nerve block combined with injection of meperidine in Neiguan point in relieving the stretch reaction during the course of gallbladder operation.

目的观察膈神经阻滞联合内关穴注射哌替啶预防胆囊手术牵拉反应的效果。

5.Jackson, a staff member said: "Meperidine injection shortly after, he began breathing very slowly, slowly becoming more and more called upon until the stop."

杰克逊，一名工作人员说：“配西汀注射后不久，他开始呼吸非常缓慢，慢慢地越来越多地呼吁，直至停止。”

6.BACKGROUND: Limited evidence supports the efficacy of intraperitoneal meperidine or local anesthetic for postoperative analgesia.

背景：很少有证据支持腹膜内注射哌替啶或局麻药用于术后镇痛是有效的。

7.AIM: To prepare the Parkinson disease models in rats with meperidine hydrochloride, and measure the neural biochemical reaction in serum.

目的：利用盐酸哌替啶制备类帕金森病大鼠模型，测定血清中神经生化反应。

8.Objective To observe the effect of diaphragm nerve block combined with injection of meperidine in Neiguan point in relieving the stretch reaction during the course of gallbladder operation.

目的观察膈神经阻滞联合内关穴注射哌替啶预防胆囊手术牵拉反应的效果。

9.Nurses are trained to monitor the effects of meperidine in patients receiving it.

护士接受培训，以监测接受美伐啶的患者的效果。

10.The doctor prescribed meperidine for the patient's severe pain management.

医生为患者的剧烈疼痛管理开了美伐啶。

11.Before the surgery, the anesthesiologist administered meperidine to help relax the patient.

在手术前，麻醉师给患者注射了美伐啶以帮助放松。

12.Due to its potential for addiction, meperidine is used cautiously in clinical settings.

由于其成瘾潜力，美伐啶在临床环境中谨慎使用。

13.Patients with a history of substance abuse may be at risk when prescribed meperidine.

有药物滥用历史的患者在被开处方美伐啶时可能面临风险。

作文

Meperidine, also known as pethidine, is a synthetic opioid analgesic that is used to treat moderate to severe pain. It was first synthesized in the 1930s and has been widely used in medical settings since then. One of the key characteristics of meperidine (美匹瑞啡) is its ability to provide rapid pain relief, making it particularly useful in acute situations such as postoperative pain management or during labor. However, like all opioids, meperidine carries risks of dependency and side effects, which healthcare providers must carefully consider when prescribing it.The mechanism of action of meperidine involves binding to the mu-opioid receptors in the brain, which are responsible for the perception of pain. By activating these receptors, meperidine alters the way the brain and nervous system respond to pain, leading to a decrease in the sensation of discomfort. This makes it an effective option for patients who may not respond well to non-opioid pain relievers.Despite its effectiveness, the use of meperidine has diminished over the years due to concerns about its safety profile. For instance, it is known to have a shorter duration of action compared to other opioids, which can lead to repeated dosing and an increased risk of side effects. Additionally, meperidine can produce toxic metabolites that may accumulate in patients with renal impairment, potentially leading to seizures and other adverse effects.Furthermore, the potential for abuse and addiction associated with meperidine cannot be overlooked. As with other opioids, there is a risk of developing tolerance, where higher doses are needed to achieve the same level of pain relief, and dependence, where patients may experience withdrawal symptoms if the medication is abruptly discontinued. Therefore, it is crucial for physicians to monitor patients closely and to consider alternative pain management strategies when appropriate.In conclusion, while meperidine (美匹瑞啡) remains a valuable tool in the arsenal of pain management, its use must be approached with caution. Healthcare professionals should weigh the benefits against the risks and consider the individual patient's needs and medical history. Education on the proper use of meperidine and awareness of its potential side effects are essential components of effective pain management. As we continue to learn more about opioids and their impact on patients, it is vital to ensure that medications like meperidine are used safely and effectively to improve patient outcomes.

美匹瑞啡，也被称为哌替啶，是一种合成的阿片类镇痛药，用于治疗中度至重度疼痛。它在20世纪30年代首次合成，自那时以来在医疗环境中被广泛使用。美匹瑞啡的一个关键特征是其提供快速疼痛缓解的能力，这使得它在急性情况下，如术后疼痛管理或分娩期间特别有用。然而，像所有阿片类药物一样，美匹瑞啡也存在依赖和副作用的风险，医疗提供者在开处方时必须仔细考虑。美匹瑞啡的作用机制涉及与大脑中的μ-阿片受体结合，这些受体负责疼痛的感知。通过激活这些受体，美匹瑞啡改变了大脑和神经系统对疼痛的反应方式，从而导致不适感的减少。这使得它成为对非阿片类止痛药反应不佳的患者的有效选择。尽管效果显著，由于对其安全性特征的担忧，美匹瑞啡的使用近年来有所减少。例如，它已知与其他阿片类药物相比，作用持续时间较短，这可能导致重复给药并增加副作用的风险。此外，美匹瑞啡可能产生毒性代谢产物，在肾功能不全的患者中可能会积累，从而导致癫痫发作和其他不良反应。此外，与美匹瑞啡相关的滥用和成瘾的潜力不容忽视。与其他阿片类药物一样，存在耐药性的发展风险，即需要更高的剂量才能达到相同的疼痛缓解水平，以及依赖性，即患者在突然停止用药时可能会出现戒断症状。因此，医生必须密切监测患者，并在适当时考虑替代的疼痛管理策略。总之，虽然美匹瑞啡（美匹瑞啡）仍然是疼痛管理工具库中的一种宝贵工具，但其使用必须谨慎对待。医疗专业人员应权衡益处与风险，并考虑个别患者的需求和病史。对美匹瑞啡的正确使用进行教育以及对其潜在副作用的认识是有效疼痛管理的重要组成部分。随着我们继续深入了解阿片类药物及其对患者的影响，确保像美匹瑞啡这样的药物安全有效地使用以改善患者结果是至关重要的。