pyrimidine

简明释义

英[,paɪ'rɪmɪ,diːn;pɪ'rɪmɪdiːn]美[paɪ'rɪmədin;pə'rɪmədiːn]

n. 嘧啶（二氮三烯陆环）

英英释义

单词用法

同义词

反义词

例句

1.Three types of N? chloroacetyl substituted nitrogen? containing benzoheterocycles were introduced into pyrimidine by the formation of thioether.

三种n-氯乙酰取代的苯并含氮杂环化合物通过硫醚键的形成被导入嘧啶结构。

2.Pyrimidine as important medicine, pesticide intermediates, application prospects are very broad.

嘧啶化合物作为重要的医药、农药中间体，应用前景非常广阔。

3.Halogenated nucleotides such as the pyrimidine analog bromodeoxyuridine (BrdU) are useful for labeling nascent DNA in living cells and tissues.

卤代核苷酸如嘧啶类似物溴脱氧尿苷(BrdU)对于新生活细胞和组织中的DNA进行标记是有用的。

4.The purine and pyrimidine may be complexed with a sugar to produce a nucleoside.

嘌呤和嘧啶可以同一个糖复合，产生一个核苷。

5.Pyrimidine rings, as the essential structure unit in biological systems, exist widely in nature.

嘧啶环广泛存在于自然界，是生命系统必须的分子结构单元。

6.Clevudine is a pyrimidine analogue with potent and sustained antiviral activity against HBV.

克来夫定为嘧啶类似物，对HBV具有持续有效的抗病毒活性。

7.Thymine: Organic compound of the pyrimidine family, often called a Base, consisting of a ring containing Both nitrogen and carbon atoms, and a methyl group.

胸腺嘧啶：一种嘧啶类有机化合物，通常叫做基底，由含有氮和碳原子以及甲基的环形物组成。

8.Uracil -- a pyrimidine found in RNA that base-pares with adenine.

尿嘧啶--核糖核酸中的一种嘧啶，与腺嘌呤形成碱基对。

9.The metabolic pathway involving pyrimidine synthesis is complex and highly regulated.

涉及嘧啶合成的代谢途径复杂且高度调控。

10.In biochemistry, pyrimidine bases are crucial components of RNA.

在生物化学中，嘧啶碱基是RNA的重要组成部分。

11.Many antiviral drugs inhibit enzymes that interact with pyrimidine nucleotides.

许多抗病毒药物抑制与嘧啶核苷酸相互作用的酶。

12.Researchers synthesized a new drug that targets pyrimidine derivatives to combat cancer.

研究人员合成了一种新药，针对嘧啶衍生物以对抗癌症。

13.The structure of pyrimidine is essential for understanding its role in nucleic acids.

了解嘧啶的结构对于理解其在核酸中的作用至关重要。

作文

In the realm of biochemistry, the understanding of nucleic acids is fundamental to grasping the complexity of life. One of the essential components of nucleic acids is the bases that make up DNA and RNA. Among these bases, one important class is known as pyrimidines. pyrimidine">嘧啶 bases include cytosine, thymine, and uracil. These molecules play crucial roles in the encoding, transmission, and expression of genetic information. The structure of pyrimidine">嘧啶 is characterized by a single six-membered ring, which contains two nitrogen atoms at positions 1 and 3, along with four carbon atoms. This simple structure allows pyrimidine">嘧啶 bases to pair effectively with purine bases, which have a more complex double-ring structure. For instance, in DNA, thymine pairs with adenine, while in RNA, uracil takes the place of thymine and pairs with adenine as well. Understanding the role of pyrimidine">嘧啶 in cellular processes is vital for many fields of research, including genetics, molecular biology, and pharmacology. The interaction between pyrimidine">嘧啶 bases and their complementary purine partners is a cornerstone of the double helix structure of DNA, which was famously described by Watson and Crick. This pairing mechanism ensures that genetic information can be accurately replicated during cell division, thereby maintaining the integrity of genetic material across generations.Moreover, the metabolism of pyrimidine">嘧啶 is equally important. The body synthesizes these bases through a series of biochemical pathways that involve various enzymes. Deficiencies or malfunctions in these pathways can lead to significant health issues. For example, disorders related to pyrimidine">嘧啶 metabolism can result in neurological problems or immune deficiencies. In addition to their biological significance, pyrimidine">嘧啶 derivatives are also utilized in the development of pharmaceuticals. Many antiviral and anticancer drugs are designed to target nucleic acid synthesis by mimicking the structure of pyrimidine">嘧啶 bases. By disrupting the normal function of these bases, such drugs can inhibit the proliferation of harmful cells, making them effective treatments for various diseases. Furthermore, the study of pyrimidine">嘧啶 extends beyond its basic biological functions. Researchers are exploring its potential in biotechnology and synthetic biology. For instance, scientists are investigating how to engineer organisms that can produce pyrimidine">嘧啶 more efficiently, which could lead to advancements in genetic engineering and synthetic genomics. In conclusion, pyrimidine">嘧啶 bases are integral to the structure and function of nucleic acids, playing a pivotal role in genetics and cellular processes. Their significance stretches from fundamental biological functions to practical applications in medicine and biotechnology. As research continues to unfold, our understanding of pyrimidine">嘧啶 and its derivatives will likely expand, revealing even more about the intricate workings of life at the molecular level.

在生物化学领域，理解核酸是掌握生命复杂性的基础。核酸的基本组成部分之一是构成DNA和RNA的碱基。在这些碱基中，有一类重要的碱基被称为pyrimidine">嘧啶。pyrimidine">嘧啶碱基包括胞嘧啶、胸腺嘧啶和尿嘧啶。这些分子在遗传信息的编码、传递和表达中发挥着至关重要的作用。pyrimidine">嘧啶的结构特点是一个六元环，其中在1位和3位上各有两个氮原子，四个碳原子。这个简单的结构使得pyrimidine">嘧啶碱基能够有效地与具有更复杂双环结构的嘌呤碱基配对。例如，在DNA中，胸腺嘧啶与腺嘌呤配对，而在RNA中，尿嘧啶取代胸腺嘧啶，与腺嘌呤配对。理解pyrimidine">嘧啶在细胞过程中的作用对许多研究领域至关重要，包括遗传学、分子生物学和药理学。pyrimidine">嘧啶碱基与其互补的嘌呤伙伴之间的相互作用是DNA双螺旋结构的基石，这一结构由沃森和克里克首次描述。这个配对机制确保了在细胞分裂过程中遗传信息可以被准确复制，从而维持了遗传物质在几代人之间的完整性。此外，pyrimidine">嘧啶的代谢同样重要。身体通过一系列涉及各种酶的生化途径合成这些碱基。这些途径中的缺陷或功能失常可能导致严重的健康问题。例如，与pyrimidine">嘧啶代谢相关的疾病可能导致神经系统问题或免疫缺陷。除了其生物学意义外，pyrimidine">嘧啶衍生物还被用于药物开发。许多抗病毒和抗癌药物旨在通过模拟pyrimidine">嘧啶碱基的结构来靶向核酸合成。通过破坏这些碱基的正常功能，这些药物可以抑制有害细胞的增殖，使它们成为各种疾病的有效治疗方法。此外，pyrimidine">嘧啶的研究不仅限于其基本生物功能。研究人员正在探索其在生物技术和合成生物学中的潜力。例如，科学家们正在研究如何工程化生物体以更高效地生产pyrimidine">嘧啶，这可能会推动基因工程和合成基因组学的发展。总之，pyrimidine">嘧啶碱基是核酸结构和功能的核心，在遗传学和细胞过程中发挥着关键作用。它们的重要性从基本生物功能延伸到医学和生物技术的实际应用。随着研究的不断展开，我们对pyrimidine">嘧啶及其衍生物的理解可能会进一步扩展，揭示出更多关于生命在分子层面上复杂运作的奥秘。