cytotoxicity

简明释义

英[/ˌsaɪtoʊˈtɑksɪsɪti/]美[/ˌsaɪtoʊˈtɑksɪsɪti/]

n. 细胞毒性

英英释义

单词用法

同义词

反义词

例句

1.The proton density weighted imaging showed that early ischemia was "cytotoxicity edema".

质子密度加权像显示早期缺血为“细胞毒性水肿”。

2.Objective to study the cytotoxicity of chitosan and its water soluble derivatives.

目的研究壳聚糖及其水溶性衍生物的细胞毒性。

3.In addition, they do not display cytotoxicity in uninfected normal cells.

此外，他们不显示细胞毒性，在未受正常细胞。

4.The main cytotoxicity and mechanisms of fumonisin were also discussed.

探讨了伏马菌素主要的细胞毒性作用及机制。

5.CONCLUSION: NO is an effector molecule in cytotoxicity of activated macrophages.

结论：NO是巨噬细胞细胞毒作用的一个效应分子。

6.They also carried out cytotoxicity tests using human cell cultures.

他们还用培养的人体细胞进行了细胞毒性测试。

7.Objective to study on the cytotoxicity of modified PP membrane.

目的研究改性后的医用聚丙烯材料的细胞毒性。

8.Objective to investigate the effect of propofol on cytotoxicity of bupivacaine on PC12 cells and its possible mechanism.

目的探讨异丙酚对布比卡因诱导的PC 12细胞毒性的作用及其可能机制。

9.The researchers conducted experiments to determine the cytotoxicity of the new drug on cancer cells.

研究人员进行了实验，以确定这种新药对癌细胞的细胞毒性。

10.High levels of cytotoxicity can lead to cell death, which is a desired effect in chemotherapy.

高水平的细胞毒性会导致细胞死亡，这在化疗中是一个理想的效果。

11.The team found that the compound showed significant cytotoxicity against various tumor cell lines.

团队发现该化合物对多种肿瘤细胞系表现出显著的细胞毒性。

12.Understanding the cytotoxicity of substances is essential for drug development.

理解物质的细胞毒性对药物开发至关重要。

13.Testing for cytotoxicity is a crucial step in assessing the safety of new pharmaceuticals.

测试细胞毒性是评估新药物安全性的关键步骤。

作文

Cytotoxicity is a term that refers to the quality of being toxic to cells. This concept is particularly significant in the fields of medicine and biology, as it plays a crucial role in understanding how certain substances can affect cellular health and function. In recent years, the study of cytotoxicity has gained considerable attention, especially in cancer research, where the goal is often to target and eliminate malignant cells without harming healthy ones. The mechanisms behind cytotoxicity can vary greatly, depending on the substance in question. For instance, chemotherapy drugs are designed to induce cytotoxicity in cancer cells, leading to their death. However, these drugs can also affect normal cells, which is why patients often experience side effects such as nausea and fatigue.Understanding the pathways that lead to cytotoxicity is essential for developing more effective treatments. Researchers are investigating various compounds that can selectively induce cytotoxicity in tumor cells while sparing healthy tissue. This selectivity is critical because it would reduce the adverse effects that many cancer therapies currently have. One promising area of research involves the use of targeted therapies, which are designed to attack specific molecular targets associated with cancer. By honing in on these targets, scientists hope to enhance cytotoxicity against cancer cells while minimizing damage to surrounding healthy cells.In addition to cancer treatment, cytotoxicity is also an important consideration in immunology. Certain immune cells, like cytotoxic T lymphocytes, are programmed to induce cytotoxicity against infected or dysfunctional cells. This natural process is vital for maintaining health and preventing the proliferation of diseases. However, when the immune system is dysregulated, it can lead to excessive cytotoxicity, resulting in autoimmune diseases where healthy cells are attacked by the body’s own immune system.Furthermore, the study of cytotoxicity extends into the realm of environmental science, where researchers examine how toxins in our environment can lead to cell damage. Chemicals found in pollutants, heavy metals, and even some pharmaceuticals can exhibit cytotoxicity, raising concerns about their impact on human health and ecosystems. Understanding the mechanisms of cytotoxicity can help in assessing risks associated with exposure to these harmful substances.In summary, cytotoxicity is a multifaceted concept with significant implications across various fields, including medicine, immunology, and environmental science. As research continues to advance, the hope is that we will be able to harness the power of cytotoxicity to develop innovative therapies that effectively combat diseases while minimizing harm to healthy cells. The ongoing exploration of this phenomenon not only enhances our understanding of cellular interactions but also paves the way for breakthroughs in treatment strategies that could improve patient outcomes and overall public health. Ultimately, the journey of understanding cytotoxicity is one that holds great promise for the future of medicine and beyond.

细胞毒性是指对细胞具有毒性的特性。这个概念在医学和生物学领域尤为重要，因为它对于理解某些物质如何影响细胞健康和功能起着至关重要的作用。近年来，细胞毒性的研究受到了相当大的关注，特别是在癌症研究中，目标通常是针对并消除恶性细胞而不伤害健康细胞。导致细胞毒性的机制可能会因所涉及的物质而异。例如，化疗药物旨在诱导癌细胞的细胞毒性，导致其死亡。然而，这些药物也可能影响正常细胞，这就是为什么患者常常经历恶心和疲劳等副作用。理解导致细胞毒性的途径对于开发更有效的治疗方法至关重要。研究人员正在调查各种化合物，这些化合物可以选择性地诱导肿瘤细胞的细胞毒性，同时保护健康组织。这种选择性至关重要，因为它将减少目前许多癌症治疗方法的副作用。一个有前景的研究领域涉及靶向治疗，这些治疗旨在攻击与癌症相关的特定分子靶标。通过聚焦于这些靶标，科学家希望增强对癌细胞的细胞毒性，同时将对周围健康细胞的损害降到最低。除了癌症治疗，细胞毒性在免疫学中也是一个重要的考虑因素。某些免疫细胞，如细胞毒性T淋巴细胞，被编程为对感染或功能失调的细胞诱导细胞毒性。这一自然过程对于维持健康和防止疾病的扩散至关重要。然而，当免疫系统失调时，可能会导致过度的细胞毒性，从而导致自身免疫疾病，在这种疾病中，身体的免疫系统攻击健康细胞。此外，细胞毒性的研究还扩展到环境科学领域，研究人员考察我们环境中的毒素如何导致细胞损伤。污染物、重金属甚至一些药物中发现的化学物质都可能表现出细胞毒性，这引发了人们对其对人类健康和生态系统影响的担忧。理解细胞毒性的机制可以帮助评估与接触这些有害物质相关的风险。总之，细胞毒性是一个多方面的概念，在医学、免疫学和环境科学等多个领域具有重要意义。随着研究的不断推进，人们希望能够利用细胞毒性的力量开发创新疗法，有效对抗疾病，同时将对健康细胞的伤害降到最低。对这一现象的持续探索不仅增强了我们对细胞相互作用的理解，还为改善患者预后和整体公共健康的治疗策略突破铺平了道路。最终，理解细胞毒性的旅程是一个充满希望的未来医学及其他领域的承诺。