mosaicism

简明释义

英[məʊˈzeɪɪˌsɪzəm]美[moʊˈzeɪɪˌsɪzəm]

n. [遗] 镶嵌性，[生物] 镶嵌现象

英英释义

单词用法

同义词

反义词

例句

1.In cytogenetics, mosaicism is also sometimes referred to as mixoploidy.

在细胞遗传学中，镶嵌性有时也称为混倍体。

2.The standard pattern distribution of normal population: Most (74.5%, 82/110) of the unrelated healthy individuals displayed such a pattern without any translocation, hybridization and mosaicism.

正常人的标准带型分布：在检测的110名正常人中，74.5％（82／110）为标准带型，无易位、杂合、体细胞嵌合等情况。

3.X chromosome mosaicism is not the only genetic difference between males and females.

染色体嵌合现象并不是男性与女性之间唯一的基因差别。

4.The standard pattern distribution of normal population: Most (74.5%, 82/110) of the unrelated healthy individuals displayed such a pattern without any translocation, hybridization and mosaicism.

正常人的标准带型分布：在检测的110名正常人中，74.5％（82／110）为标准带型，无易位、杂合、体细胞嵌合等情况。

5.Female mosaicism of the X chromosome has major implications for human health and disease and is the leading cause of female protection from X-linked genetic disorders.

女性作为X染色体的杂合子在人类的健康与疾病中及重要作用，并可避免X连锁遗产性疾病在女性中发生。

6.Researchers are investigating how mosaicism affects the severity of certain genetic conditions.

研究人员正在调查镶嵌体如何影响某些遗传病的严重程度。

7.The presence of mosaicism in skin cells can result in a patchy appearance, often seen in certain skin disorders.

皮肤细胞中的镶嵌体会导致斑驳的外观，常见于某些皮肤疾病。

8.The study of genetic disorders often includes the concept of mosaicism, which refers to the presence of two or more genetically different cell lines in the same individual.

对遗传疾病的研究通常包括镶嵌体的概念，即同一个体内存在两种或多种不同的细胞系。

9.In some cases of cancer, mosaicism can lead to the development of tumors with varying genetic mutations.

在某些癌症病例中，镶嵌体可能导致具有不同遗传突变的肿瘤的发展。

10.Understanding mosaicism is crucial for genetic counseling, especially for families with a history of genetic disorders.

理解镶嵌体对遗传咨询至关重要，尤其是对于有遗传病史的家庭。

作文

Mosaicism is a fascinating biological phenomenon that occurs when an individual has two or more genetically different cell lines within their body. This can happen during early embryonic development, where a mutation occurs in one of the cells, leading to a situation where some cells carry the mutation while others do not. The term mosaicism (拼图体) draws its name from the idea that the organism's cells are like pieces of a mosaic, each contributing to the overall picture but differing in color and pattern. Understanding mosaicism (拼图体) is crucial for comprehending various genetic disorders and developmental conditions. For instance, individuals with Turner syndrome may exhibit mosaicism (拼图体), where some cells have the typical two X chromosomes while others have only one. This leads to a wide range of symptoms and varying degrees of severity in the condition. The implications of mosaicism (拼图体) extend beyond genetics into fields such as medicine and psychology. In medical genetics, recognizing the presence of mosaicism (拼图体) can significantly influence diagnosis and treatment options. For example, if a patient presents with a genetic disorder, understanding whether they exhibit mosaicism (拼图体) can help doctors predict the progression of the disease and tailor interventions accordingly. Moreover, mosaicism (拼图体) challenges traditional views of inheritance. It highlights the complexity of genetic expression and the fact that not all cells in a person's body will express the same genetic information. This can lead to situations where a person may not show symptoms of a genetic disorder despite having cells that carry the mutation. In addition to its medical significance, mosaicism (拼图体) also raises intriguing questions about identity and individuality. If an individual consists of genetically distinct cell lines, what does that mean for their sense of self? Are they fundamentally the same person if parts of their body are genetically different? These questions touch on philosophical discussions about the nature of being and the essence of identity. Research into mosaicism (拼图体) continues to evolve, with scientists exploring its role in cancer development. Many tumors exhibit mosaicism (拼图体), characterized by a mix of cancerous and non-cancerous cells. Understanding how mosaicism (拼图体) contributes to tumor heterogeneity could pave the way for more effective cancer treatments. In conclusion, mosaicism (拼图体) is a complex and multifaceted concept that plays a significant role in genetics, medicine, and our understanding of identity. As research progresses, we will likely uncover more about how mosaicism (拼图体) influences health and disease, leading to advancements in personalized medicine and genetic counseling. The study of mosaicism (拼图体) not only deepens our understanding of biological diversity but also prompts us to reflect on the intricate tapestry of life itself.

拼图体是一个迷人的生物现象，发生在个体身体内有两种或多种基因不同的细胞系。它可能在早期胚胎发育期间发生，当时某个细胞发生突变，导致一些细胞携带突变，而其他细胞则不携带。术语拼图体（mosaicism）源于这样的想法：生物体的细胞就像拼图的碎片，每个碎片都对整体图像做出贡献，但在颜色和图案上有所不同。理解拼图体（mosaicism）对于理解各种遗传疾病和发育状况至关重要。例如，患有特纳综合征的个体可能表现出拼图体（mosaicism），其中一些细胞具有典型的两个X染色体，而其他细胞只有一个。这导致症状的广泛变化和病情严重程度的不同。拼图体（mosaicism）的影响不仅限于医学，还扩展到心理学等领域。在医学遗传学中，认识到拼图体（mosaicism）的存在可以显著影响诊断和治疗方案。例如，如果患者表现出遗传疾病，了解他们是否表现出拼图体（mosaicism）可以帮助医生预测疾病的进展并相应地量身定制干预措施。此外，拼图体（mosaicism）挑战了传统的遗传观念。它突显了基因表达的复杂性以及一个人身体中的所有细胞并不会表达相同的遗传信息。这可能导致一种情况，即一个人尽管身体的一部分携带突变，但并未表现出遗传疾病的症状。除了医学意义外，拼图体（mosaicism）还引发了有关身份和个体性的有趣问题。如果一个个体由基因上不同的细胞系组成，那么这对他们的自我意识意味着什么？如果他们身体的某些部分在基因上不同，他们是否仍然是同一个人？这些问题涉及关于存在的哲学讨论，以及身份的本质。对拼图体（mosaicism）的研究仍在不断发展，科学家们正在探索它在癌症发展中的作用。许多肿瘤表现出拼图体（mosaicism），其特征是癌细胞和非癌细胞的混合。理解拼图体（mosaicism）如何促成肿瘤异质性可能为更有效的癌症治疗铺平道路。总之，拼图体（mosaicism）是一个复杂而多面的概念，在遗传学、医学和我们对身份的理解中发挥着重要作用。随着研究的进展，我们可能会发现更多关于拼图体（mosaicism）如何影响健康和疾病的信息，从而推动个性化医疗和遗传咨询的进步。对拼图体（mosaicism）的研究不仅加深了我们对生物多样性的理解，还促使我们反思生命本身的复杂拼图。