ribonuclease

简明释义

英[ˌraɪbə(ʊ)ˈnjuːklɪeɪz]美[ˌraɪboˈnjʊklɪez]

n. [生化] 核糖核酸酶

英英释义

单词用法

同义词

反义词

例句

1.Construction of HBV targeted ribonuclease and its expression in 2.2.15 cell line.

HBV靶向核糖核酸酶真核表达载体的构建及其在2.2.15细胞内的表达。

2.Objective: To detect the expression of ribonuclease inhibitor (RI) in the serum of patients with malignant tumors by indirect ELISA.

目的：探讨间接酶联免疫吸附试验（ELISA）检测核糖核酸酶抑制因子（RI）在恶性肿瘤患者血清中的表达。

3.For example, by random folding, the amino-acid chain of the enzyme ribonuclease, a small protein, could adopt more than 1040 different shapes, which would take billions of years to explore.

例如，通过随机折叠，核糖核酸酶(一种小型蛋白质)的氨基酸链能形成超过1040种不同的结构，单这一种蛋白质就需要数亿年的时间来探索。

4.AIM: to prepare and purify the antibody against ribonuclease inhibitor (ri).

目的：制备并纯化抗核糖核酸酶抑制因子(RI)的抗体。

5.Has discussed in initially the frog egg the ribonuclease active constituent.

初步探讨了蛙卵中核糖核酸酶的活性组分。

6.Human pancreatic ribonuclease has 128 amino acid residues.

人的胰腺核糖核酸酶有128个氨基酸残基。

7.Mass spectra of proteins such as ribonuclease A and lysozyme were obtained with substantially enhanced abundant peaks of low charge states.

采用核糖核酸A、溶菌酶等样品和商品化的线性离子阱质谱仪对该电离源进行了表征。

8.For example, by random folding, the amino-acid chain of the enzyme ribonuclease, a small protein, could adopt more than 1040 different shapes, which would take billions of years to explore.

例如，通过随机折叠，核糖核酸酶(一种小型蛋白质)的氨基酸链能形成超过1040种不同的结构，单这一种蛋白质就需要数亿年的时间来探索。

9.Objective: to explore the role and mechanism of suppression of ribonuclease RNase inhibitor in the growth of glioma cells.

目的：探讨核糖核酸酶抑制因子对脑胶质瘤生长的抑制作用及可能机理。

10.Researchers are studying the role of ribonuclease in viral infections.

研究人员正在研究核糖核酸酶在病毒感染中的作用。

11.Inhibitors of ribonuclease are being developed as potential therapeutic agents.

针对核糖核酸酶的抑制剂正在开发作为潜在的治疗药物。

12.The study showed that ribonuclease activity varies among different tissues.

研究表明，不同组织中的核糖核酸酶活性有所不同。

13.The presence of ribonuclease can affect the stability of RNA molecules.

存在核糖核酸酶可能会影响RNA分子的稳定性。

14.The enzyme ribonuclease is crucial for RNA degradation in cells.

酶核糖核酸酶对细胞中的RNA降解至关重要。

作文

Ribonuclease, often abbreviated as RNase, is an essential enzyme that plays a crucial role in the metabolism of RNA within living organisms. This enzyme catalyzes the degradation of RNA into smaller components, which are subsequently utilized for various cellular processes. Understanding the function and importance of ribonuclease (核糖核酸酶) is vital for researchers studying molecular biology, genetics, and biochemistry.The primary function of ribonuclease (核糖核酸酶) is to cleave the phosphodiester bonds between the nucleotide units of RNA. This activity is significant because it helps regulate the levels of RNA in cells, ensuring that only the necessary amounts are present for protein synthesis and other functions. By breaking down excess or damaged RNA, ribonuclease (核糖核酸酶) contributes to the maintenance of cellular homeostasis.There are several types of ribonuclease (核糖核酸酶), each with distinct properties and functions. For instance, some RNases are specific to certain types of RNA, such as messenger RNA (mRNA), while others can degrade various RNA substrates. The diversity among these enzymes allows cells to finely tune their RNA metabolism according to their needs. This specificity is particularly important during cellular stress responses, where the regulation of RNA levels can determine cell survival or apoptosis.In addition to their role in RNA metabolism, ribonuclease (核糖核酸酶) enzymes have been studied for their potential therapeutic applications. For example, certain RNases exhibit anti-tumor properties and are being investigated as potential cancer treatments. These enzymes can selectively target and degrade the RNA of cancer cells, leading to reduced proliferation and increased cell death. This targeted approach minimizes damage to healthy cells and represents a promising avenue for developing new cancer therapies.Moreover, ribonuclease (核糖核酸酶) is also utilized in laboratory settings for various applications. Researchers often employ RNases to remove RNA contamination from DNA preparations, which is crucial for accurate genetic analyses. The ability to selectively degrade RNA without affecting DNA makes ribonuclease (核糖核酸酶) an invaluable tool in molecular biology laboratories.Despite its numerous benefits, the activity of ribonuclease (核糖核酸酶) must be carefully regulated within cells. Overactivity of this enzyme can lead to detrimental effects, such as the rapid degradation of essential RNA molecules, which may impair cellular function. Therefore, cells have evolved multiple mechanisms to control the expression and activity of ribonuclease (核糖核酸酶), ensuring that RNA degradation occurs at the right time and place.In conclusion, ribonuclease (核糖核酸酶) is a pivotal enzyme that facilitates the breakdown of RNA, thereby playing a significant role in maintaining RNA homeostasis and regulating gene expression. Its diverse forms and applications in both biological processes and medical research highlight its importance in modern science. As we continue to explore the functions of ribonuclease (核糖核酸酶), we may uncover even more ways in which this enzyme can be harnessed for therapeutic purposes and enhance our understanding of cellular mechanisms.

核糖核酸酶，通常简称为RNase，是一种重要的酶，在生物体内RNA的代谢中发挥着至关重要的作用。这种酶催化RNA降解成更小的成分，这些成分随后被用于各种细胞过程。理解ribonuclease（核糖核酸酶）的功能和重要性对研究分子生物学、遗传学和生物化学的研究人员至关重要。ribonuclease（核糖核酸酶）的主要功能是切割RNA的磷酸二酯键。这一活动是重要的，因为它有助于调节细胞内RNA的水平，确保仅存在必要数量的RNA以进行蛋白质合成和其他功能。通过分解过量或损坏的RNA，ribonuclease（核糖核酸酶）有助于维持细胞的稳态。有几种类型的ribonuclease（核糖核酸酶），每种都有不同的特性和功能。例如，一些RNase专门针对某些类型的RNA，如信使RNA（mRNA），而其他则可以降解各种RNA底物。这些酶之间的多样性使细胞能够根据需要精细调整其RNA代谢。这种特异性在细胞应激反应期间尤为重要，此时RNA水平的调节可以决定细胞存活或凋亡。除了在RNA代谢中的作用外，ribonuclease（核糖核酸酶）酶还因其潜在的治疗应用而受到研究。例如，某些RNase表现出抗肿瘤特性，正在作为潜在的癌症治疗方法进行研究。这些酶可以选择性地靶向并降解癌细胞的RNA，从而减少增殖并增加细胞死亡。这种靶向方法最小化了对健康细胞的损害，代表了开发新型癌症疗法的有前景的途径。此外，ribonuclease（核糖核酸酶）在实验室环境中也被用于各种应用。研究人员经常使用RNase去除DNA制备中的RNA污染，这对于准确的遗传分析至关重要。选择性降解RNA而不影响DNA的能力使得ribonuclease（核糖核酸酶）成为分子生物学实验室中的宝贵工具。尽管有许多好处，但ribonuclease（核糖核酸酶）的活性必须在细胞内得到仔细调节。该酶的过度活性可能导致不良影响，例如必需RNA分子的快速降解，这可能损害细胞功能。因此，细胞已经进化出多种机制来控制ribonuclease（核糖核酸酶）的表达和活性，确保RNA降解在正确的时间和地点发生。总之，ribonuclease（核糖核酸酶）是一种关键酶，促进RNA的降解，从而在维持RNA稳态和调节基因表达中发挥重要作用。它在生物过程和医学研究中的多样性形式和应用突显了其在现代科学中的重要性。随着我们继续探索ribonuclease（核糖核酸酶）的功能，我们可能会发现更多利用这种酶的治疗方法，并增强我们对细胞机制的理解。