amidase

简明释义

英[ˈæmɪˌdeɪz]美[ˈæmɪˌdeɪs;ˈæmɪˌdeɪz]

n. [生化] 酰胺酶

英英释义

单词用法

同义词

反义词

例句

1.A novel enantioselective amidase screening system was developed and proved to be efficient and accurate.

论文首先建立了一种新的立体选择性酰胺酶的筛选模型。

2.In specific embodiments, the invention provides methods for inducing and stabilizing nitrile hydratase activity, amidase activity, and asparaginase I activity.

在具体实施方式中，本发明提供了用于诱导和稳定腈水合酶活性、酰胺酶活性和天冬酰胺酶I活性的方法。

3.In specific embodiments, the invention provides methods for inducing and stabilizing nitrile hydratase activity, amidase activity, and asparaginase I activity.

在具体实施方式中，本发明提供了用于诱导和稳定腈水合酶活性、酰胺酶活性和天冬酰胺酶I活性的方法。

4.Scientists have isolated a new strain of bacteria that produces amidase efficiently.

科学家们分离出一种高效产生amidase的新细菌株。

5.The presence of amidase in soil helps in the degradation of organic pollutants.

土壤中存在的amidase有助于有机污染物的降解。

6.In the laboratory, we measured the activity of amidase under various pH conditions.

在实验室中，我们测量了不同pH条件下amidase的活性。

7.The enzyme amidase plays a crucial role in the breakdown of amides in biochemical processes.

酶amidase在生化过程中分解酰胺中起着关键作用。

8.Researchers are studying how amidase can be used to improve drug metabolism.

研究人员正在研究如何利用amidase来改善药物代谢。

作文

In the realm of biochemistry, enzymes play a crucial role in facilitating various biochemical reactions. One such enzyme that has garnered attention is amidase, which is known for its ability to hydrolyze amides into their corresponding acids and ammonia. The significance of amidase lies not only in its biological functions but also in its applications across various industries, including pharmaceuticals and agriculture. Understanding how amidase operates can provide insights into metabolic processes and the development of new therapeutic strategies.Amidases are enzymes that catalyze the conversion of amides, which are organic compounds containing a carbonyl group linked to a nitrogen atom, into carboxylic acids and ammonia. This reaction is vital in many biological systems, as it helps regulate nitrogen levels and facilitates the breakdown of complex molecules. For instance, in microbial metabolism, amidase aids in the utilization of nitrogen sources by breaking down amides present in the environment. This process not only contributes to nutrient cycling but also supports the growth of microorganisms that play essential roles in ecosystems.The mechanism of action of amidase involves the formation of a tetrahedral intermediate, which subsequently leads to the release of the acid and ammonia. This enzymatic activity is influenced by various factors, including pH, temperature, and the presence of cofactors. Researchers have been keen to explore the structural properties of amidase to better understand its catalytic efficiency and specificity. Techniques such as X-ray crystallography and nuclear magnetic resonance spectroscopy have been employed to elucidate the three-dimensional structure of this enzyme, revealing the active site where the substrate binds.Beyond its biological relevance, amidase has practical applications in biotechnology and industry. In the pharmaceutical sector, it is utilized in drug development processes, particularly in the synthesis of amine-containing compounds. By employing amidase, chemists can create more efficient pathways for drug synthesis, ultimately leading to more effective medications with reduced side effects. Additionally, amidase is used in the agricultural industry for the production of bio-based fertilizers, as it helps break down organic matter and release nutrients necessary for plant growth.Moreover, the study of amidase has implications for environmental sustainability. As the world faces challenges related to waste management and pollution, enzymes like amidase offer a greener alternative for the degradation of harmful substances. By harnessing the power of amidase, scientists are exploring ways to develop bioremediation strategies that utilize microbes capable of breaking down pollutants, thereby contributing to cleaner environments.In conclusion, amidase is a remarkable enzyme with diverse applications and significant biological functions. Its ability to hydrolyze amides makes it an essential component in various metabolic pathways and industrial processes. As research continues to unveil the complexities of amidase, we can expect to see advancements in biotechnology, pharmaceuticals, and environmental science, highlighting the importance of understanding such enzymes in our quest for innovation and sustainability.

在生物化学领域，酶在促进各种生化反应中发挥着关键作用。其中一种备受关注的酶是amidase，它以能够将酰胺水解为相应的酸和氨而闻名。amidase的重要性不仅体现在其生物功能上，还体现在其在制药和农业等多个行业的应用中。理解amidase的运作方式可以提供对代谢过程的深入见解，并为新治疗策略的发展提供思路。酰胺酶是一种催化酰胺（即含有羰基与氮原子相连的有机化合物）转化为羧酸和氨的酶。这一反应在许多生物系统中至关重要，因为它有助于调节氮水平，并促进复杂分子的分解。例如，在微生物代谢中，amidase通过分解环境中的酰胺来帮助利用氮源。这个过程不仅有助于养分循环，还支持在生态系统中发挥重要作用的微生物的生长。amidase的作用机制涉及四面体中间体的形成，随后导致酸和氨的释放。这种酶活性受到多种因素的影响，包括pH、温度和辅因子的存在。研究人员一直热衷于探索amidase的结构特性，以更好地理解其催化效率和特异性。诸如X射线晶体学和核磁共振光谱等技术已被用于阐明该酶的三维结构，揭示了底物结合的活性位点。除了生物相关性外，amidase在生物技术和工业中的实际应用也十分广泛。在制药行业，它被用于药物开发过程中，特别是在含氨基化合物的合成中。通过采用amidase，化学家可以创建更高效的药物合成途径，最终导致更有效的药物并减少副作用。此外，amidase还用于农业行业，用于生产生物基肥料，因为它有助于分解有机物质并释放植物生长所需的养分。此外，对amidase的研究对环境可持续性具有重要意义。随着世界面临废物管理和污染相关的挑战，像amidase这样的酶为有害物质的降解提供了更环保的替代方案。通过利用amidase的力量，科学家们正在探索开发利用能够分解污染物的微生物的生物修复策略，从而有助于实现更清洁的环境。总之，amidase是一种具有多样应用和重要生物功能的非凡酶。它水解酰胺的能力使其成为各种代谢通路和工业过程中的重要组成部分。随着研究继续揭示amidase的复杂性，我们可以期待在生物技术、制药和环境科学方面的进展，突显出理解这些酶在我们追求创新和可持续发展中的重要性。