diazomethane

简明释义

英[daɪˌeɪzəʊˈmiːθeɪn]美[daɪˌæzoʊˈmeθeɪn]

n. [有化] 重氮甲烷

英英释义

单词用法

同义词

反义词

例句

1.Experimental comparison was also made between the continuous bubble method and the intermittent bubble method of diazomethane.

对重氮甲烷连续鼓泡法和间断鼓泡法进行了试验对比。

2.By adopting the self-designed diazomethane generating device, the dosage of reaction reagent of diazald was effectively controlled and the harmful gas release was reduced.

采用自行设计制造的重氮甲烷发生装置，有效控制了二甲基亚硝基苯磺酰胺的反应用量，减少了有害气体的排放。

3.The paper described the method of making diazomethane and its corresponding apparatus by using common items in the lab. All the required materials were low cost and easy to obtain.

文章介绍了利用实验室常见物品制作简易重氮甲烷发生和反应装置的步骤。

4.Under mild reaction condition, the derivative reaction of diazomethane with acid herbicides occurred and produced ester compounds with little by-products, which could be easily detected by GC-MS.

重氮甲烷与酸性除草剂发生衍生反应，生成易于气相色谱-质谱测定的酯类化合物，反应条件温和，副产物少。

5.Under mild reaction condition, the derivative reaction of diazomethane with acid herbicides occurred and produced ester compounds with little by-products, which could be easily detected by GC-MS.

重氮甲烷与酸性除草剂发生衍生反应，生成易于气相色谱-质谱测定的酯类化合物，反应条件温和，副产物少。

6.The reaction of carboxylic acids with diazomethane produces methyl esters.

羧酸与二氮甲烷反应生成甲基酯。

7.In organic chemistry, diazomethane is often used as a reagent for methylation.

在有机化学中，二氮甲烷通常用作甲基化试剂。

8.Safety precautions are essential when handling diazomethane due to its high toxicity.

处理二氮甲烷时必须采取安全预防措施，因为它具有高度毒性。

9.Researchers used diazomethane to prepare various derivatives in their study.

研究人员在他们的研究中使用二氮甲烷制备了各种衍生物。

10.The synthesis of methyl esters can be efficiently carried out using diazomethane.

使用二氮甲烷可以高效合成甲基酯。

作文

In the world of organic chemistry, certain compounds play pivotal roles in various reactions and syntheses. One such compound is diazomethane, a colorless gas that is both highly reactive and incredibly useful in the field of chemical research. The significance of diazomethane lies in its ability to generate methyl esters from carboxylic acids, making it an essential reagent for chemists looking to modify organic compounds. This reaction is particularly valuable because it allows for the transformation of functional groups, enabling scientists to explore new pathways for synthesis and application.Diazomethane is synthesized through the reaction of nitrous acid with a suitable precursor, often involving the use of methyl hydrazine or other nitrogen-containing compounds. The process requires careful handling due to the compound's inherent instability and toxicity. When exposed to heat or light, diazomethane can decompose explosively, which necessitates the use of specialized equipment and safety precautions in the laboratory.One of the most notable applications of diazomethane is in the realm of carbohydrate chemistry. Researchers often employ diazomethane to methylate hydroxyl groups on sugar molecules, facilitating the study of their structure and reactivity. By converting alcohols into their corresponding methyl ethers, scientists can gain insights into the behavior of these molecules in biological systems. This methylation process is not only crucial for understanding fundamental biochemical pathways but also for developing pharmaceutical agents that target specific enzymes and receptors.Moreover, diazomethane is utilized in the synthesis of various natural products and complex organic molecules. Its ability to introduce methyl groups selectively makes it a valuable tool in the construction of intricate molecular architectures. For instance, in the synthesis of certain alkaloids and terpenes, diazomethane serves as a key intermediate that helps to build the desired structure while minimizing unwanted side reactions.However, the use of diazomethane is not without its challenges. Due to its toxicity, proper ventilation and protective gear are imperative when working with this compound. Additionally, researchers must be aware of the potential for side reactions that can occur if diazomethane is not handled under strictly controlled conditions. As a result, many laboratories have established protocols to ensure the safe and efficient use of this reagent.In conclusion, diazomethane is a remarkable compound that has earned its place in the toolbox of organic chemists. Its unique properties and reactivity make it indispensable for a variety of synthetic applications, particularly in the modification of organic molecules. As research continues to advance, the role of diazomethane in the development of new drugs and materials will likely expand, highlighting the ongoing importance of this fascinating compound in the field of chemistry. Understanding how to effectively utilize diazomethane can lead to significant breakthroughs in both academic and industrial settings, demonstrating the profound impact that such a small molecule can have on the larger scientific community.

在有机化学的世界中，某些化合物在各种反应和合成中发挥着关键作用。其中一个化合物是diazomethane，一种无色气体，既高度反应性又在化学研究领域中极为有用。diazomethane的重要性在于它能够从羧酸生成甲基酯，这使其成为化学家修改有机化合物时必不可少的试剂。这一反应尤其有价值，因为它允许功能团的转化，使科学家能够探索合成和应用的新途径。Diazomethane通过亚硝酸与合适前体的反应合成，通常涉及使用甲基肼或其他含氮化合物。由于该化合物固有的不稳定性和毒性，该过程需要小心处理。当暴露于热或光时，diazomethane可能会爆炸性分解，这需要在实验室中使用专用设备和安全预防措施。Diazomethane最显著的应用之一是在碳水化合物化学领域。研究人员通常利用diazomethane对糖分子上的羟基进行甲基化，从而便于研究其结构和反应性。通过将醇转化为相应的甲基醚，科学家可以深入了解这些分子在生物系统中的行为。这一甲基化过程不仅对理解基本生化途径至关重要，而且对开发针对特定酶和受体的药物具有重要意义。此外，diazomethane还被用于合成各种天然产物和复杂的有机分子。其选择性引入甲基的能力使其成为构建复杂分子结构的宝贵工具。例如，在某些生物碱和萜类化合物的合成中，diazomethane作为关键中间体，有助于构建所需的结构，同时最小化不必要的副反应。然而，使用diazomethane并非没有挑战。由于其毒性，在使用该化合物时必须确保良好的通风和个人防护装备。此外，研究人员必须意识到如果diazomethane未在严格控制的条件下处理，可能会发生的副反应。因此，许多实验室制定了确保安全有效使用这一试剂的协议。总之，diazomethane是一种出色的化合物，已在有机化学家的工具箱中占据了一席之地。其独特的性质和反应性使其在各种合成应用中不可或缺，特别是在有机分子的修饰中。随着研究的不断进展，diazomethane在新药物和材料开发中的作用可能会扩大，突显出这一迷人化合物在化学领域的持续重要性。理解如何有效利用diazomethane可以带来学术和工业环境中的重大突破，展示了这样一个小分子对更大科学共同体的深远影响。