oncogenicity

简明释义

英[ˌɒŋkəʊdʒəˈnɪsɪti]美[ˌɑːŋkoʊdʒəˈnɪsəti]

n. 致肿瘤性

英英释义

单词用法

同义词

反义词

例句

1.The nude mouse transplantation tumor experiment displayed that the oncogenicity of sp cells was higher than that of NSP cells.

裸鼠成瘤实验显示SP细胞的致瘤能力明显高于NSP细胞。

2.CONCLUSION: Acellular matrix bone displays good biocompatibility, low antigenicity, and no cytotoxicity or oncogenicity.

结论：脱细胞基质骨具有良好的生物相容性、极低的抗原性、无细胞毒性和致瘤性。

3.Conclusion: Transfection of DTA gene in vitro may kill human lung adenocarcinoma cells and reduce the oncogenicity of human lung adenocarcinoma cells.

结论体外转染白喉毒素a基因可杀伤人肺腺癌细胞并降低人肺腺癌细胞的致瘤性。

4.Objective to study the Oncogenicity of rat EL4 lymphoma cell transfected with gene B71 and to provide experimental basis for preparing tumor vaccine by transfected gene.

目的研究b 71基因转染小鼠el4淋巴瘤细胞的致瘤性，为制备基因转染瘤苗提供实验依据。

5.Clone formation test was used to detect oncogenicity in vitro.

软琼脂克隆实验检测细胞体外成瘤性；

6.Objective To study oncogenicity in several microencapsulated cells 'xenograft.

目的探讨微囊化技术对细胞异种移植致瘤性的影响。

7.Objective to study the Oncogenicity of rat EL4 lymphoma cell transfected with gene B71 and to provide experimental basis for preparing tumor vaccine by transfected gene.

目的研究b 71基因转染小鼠el4淋巴瘤细胞的致瘤性，为制备基因转染瘤苗提供实验依据。

8.Scientists are developing tests to evaluate the oncogenicity 致癌性 of new pharmaceutical compounds before they enter clinical trials.

科学家们正在开发测试，以评估新药物化合物在进入临床试验之前的致癌性 oncogenicity。

9.The researchers are studying the oncogenicity 致癌性 of certain viruses to understand how they contribute to cancer development.

研究人员正在研究某些病毒的致癌性 oncogenicity，以了解它们如何促进癌症的发展。

10.Understanding the mechanisms of oncogenicity 致癌性 can lead to better prevention strategies for cancer.

理解致癌性 oncogenicity的机制可以为癌症的更好预防策略提供帮助。

11.The study focused on the oncogenicity 致癌性 of certain genetic mutations in breast cancer patients.

该研究集中在乳腺癌患者中某些基因突变的致癌性 oncogenicity上。

12.The findings suggest a strong link between the oncogenicity 致癌性 of the chemical and the increased risk of lung cancer.

研究结果表明，该化学物质的致癌性 oncogenicity与肺癌风险增加之间存在密切联系。

作文

The study of cancer has evolved significantly over the past few decades, leading to a deeper understanding of the mechanisms that drive this complex disease. One important aspect of cancer research is the concept of oncogenicity, which refers to the ability of certain agents, such as viruses or chemicals, to cause cancer. This term is derived from the word 'oncogene,' which denotes a gene that has the potential to induce cancer when mutated or expressed at high levels. Understanding oncogenicity is crucial for developing targeted therapies and preventive strategies against various types of cancer.One of the most well-known examples of oncogenicity is seen in certain strains of the human papillomavirus (HPV). These viral strains have been linked to cervical cancer and other malignancies. The mechanism by which HPV exerts its oncogenicity involves the integration of viral DNA into the host genome, leading to the disruption of normal cellular regulatory pathways. This results in uncontrolled cell proliferation and ultimately, tumor formation. As researchers continue to investigate the oncogenicity of HPV, vaccines have been developed to prevent infection with high-risk strains, significantly reducing the incidence of cervical cancer worldwide.Another area of interest in the study of oncogenicity is the role of environmental carcinogens. Substances such as tobacco smoke, asbestos, and certain chemicals used in industrial processes have been shown to possess oncogenicity. For instance, benzene, a common industrial chemical, has been linked to leukemia due to its ability to cause mutations in the DNA of hematopoietic stem cells. Understanding how these carcinogens interact with cellular mechanisms helps scientists devise strategies to mitigate their effects and protect public health.Furthermore, the concept of oncogenicity extends to genetic predispositions as well. Some individuals inherit mutations in specific genes, such as BRCA1 and BRCA2, which significantly increase their risk of developing breast and ovarian cancers. Research into the oncogenicity associated with these mutations has led to the development of genetic testing and personalized medicine approaches, allowing for early detection and preventive measures tailored to individual risk profiles.In conclusion, the term oncogenicity encapsulates a critical aspect of cancer research, highlighting the various factors that contribute to the initiation and progression of cancer. By studying the oncogenicity of different agents, including viruses, environmental toxins, and genetic mutations, researchers aim to unravel the complexities of cancer biology. This knowledge not only enhances our understanding of the disease but also paves the way for innovative treatments and preventive strategies, ultimately improving patient outcomes and reducing the burden of cancer globally.

癌症研究在过去几十年中显著发展，导致我们对驱动这一复杂疾病的机制有了更深入的理解。癌症研究的一个重要方面是致癌性的概念，它指的是某些因子（如病毒或化学物质）引起癌症的能力。这个术语源于“癌基因”一词，表示一种在突变或高水平表达时具有诱发癌症潜力的基因。理解致癌性对于开发针对各种类型癌症的靶向治疗和预防策略至关重要。最著名的致癌性例子之一是某些人乳头瘤病毒（HPV）毒株。这些病毒毒株与宫颈癌及其他恶性肿瘤有关。HPV施加其致癌性的机制涉及将病毒DNA整合到宿主基因组中，从而导致正常细胞调控途径的破坏。这导致细胞不受控制地增殖，最终形成肿瘤。随着研究人员继续调查HPV的致癌性，疫苗已经被开发出来以预防高风险毒株感染，从而显著降低全球宫颈癌的发病率。在致癌性研究的另一个兴趣领域是环境致癌物的作用。烟草烟雾、石棉和某些工业过程中使用的化学物质等物质已被证明具有致癌性。例如，苯是一种常见的工业化学品，与白血病有关，因为它能够导致造血干细胞DNA中的突变。了解这些致癌物如何与细胞机制相互作用有助于科学家制定减轻其影响和保护公共健康的策略。此外，致癌性的概念还扩展到遗传易感性。一些个体遗传特定基因中的突变，如BRCA1和BRCA2，这显著增加了他们患乳腺癌和卵巢癌的风险。对这些突变相关的致癌性的研究导致了基因检测和个性化医学方法的发展，使得早期检测和针对个体风险特征的预防措施成为可能。总之，术语致癌性概括了癌症研究的一个关键方面，突出了促成癌症发生和进展的各种因素。通过研究不同因子的致癌性，包括病毒、环境毒素和遗传突变，研究人员旨在揭示癌症生物学的复杂性。这一知识不仅增强了我们对疾病的理解，也为创新治疗和预防策略铺平了道路，最终改善患者的预后并减少全球癌症负担。