fibrotic

简明释义

英[faɪˈbrɒtɪk]美[faɪbˈrɑːtɪk]

adj. 纤维化的；[病理] 纤维变性的

英英释义

单词用法

同义词

反义词

例句

1.The results suggested that ILK might be involved in fibrotic process or senescent process in aging kidney.

提示整合素连接激酶可能涉及到老龄肾脏的纤维化过程或衰老过程。

2.CTGF was mainly expressed in portal tracts and fibrotic areas. Positive staining was observed in hepatic stellate cells, sinusoidal endothelial cells and fibroblasts.

CTGF的表达主要集中于汇管区和纤维化区，肝星状细胞、成纤维细胞和窦状隙内皮细胞染色常呈阳性。

3.Results: Among the 34 SARS patients, 18 revealed fibrotic changes of various extent in the lungs while staying in the hospital.

结果：34例SARS患者中18例在住院时期肺部有不同程度的纤维化改变。

4.In 6 patients (10%), the arterial contrast enhancement pattern could not be determined because of the very small size of the lesions or fibrotic nodules.

在6例(10%)病人中，由于病变很小或纤维结节的原因，动脉期增强模式不能确定。

5.At high magnification, the renal arteries with chronic vascular rejection are markedly thickened and fibrotic.

高倍镜下，慢性血管排斥反应引起肾动脉显著增厚和纤维化。

6.Recently, a newly identified cell type, the fibrocyte, has been reported to contribute to wound healing and fibrotic conditions such as hypertrophic scarring.

近年来，循环成纤维细胞作为一种新型细胞被发现并鉴定，有报道表明这种细胞对创伤愈合和类似瘢痕肥大的纤维变性具有促进作用。

7.Conclusion: Hyperglycemia for 8 weeks can change the REDOX homeostasis in liver, but can not aggravate the oxidative injury in inflammatory or fibrotic liver.

结论：8周的高血糖可能一定程度的改变肝脏的氧化还原状态，但这种改变不够明显。在并发肝脏炎症时，高血糖不能进一步加重肝脏的氧化打击。

8.Besides relic hepatic carcinoma cells were detected only in 3 nodes in group a, fibrotic scar and necrotic tissue were evident in all other nodes.

细针活检除a组3个结节内见残留肝癌细胞外，余均为纤维瘢痕组织及坏死组织。

9.Overexposure to vapor, dust or mist may aggravate existing respiratory conditions, such as asthma, bronchitis, and inflammatory or fibrotic respiratory disease.

过度暴露于蒸气，尘埃或雾气可能会加重原有的呼吸条件，如哮喘，支气管炎，炎症或纤维化呼吸系统疾病。

10.Doctors are exploring new treatments to reverse fibrotic 纤维化的 changes in the liver.

医生们正在探索新的治疗方法，以逆转肝脏中的纤维化的变化。

11.The patient was diagnosed with a fibrotic 纤维化的 lung condition that made breathing difficult.

患者被诊断为患有一种使呼吸困难的纤维化的肺部疾病。

12.A biopsy revealed fibrotic 纤维化的 lesions in the patient's skin.

活检显示患者皮肤中有纤维化的病变。

13.Research shows that fibrotic 纤维化的 tissue can lead to organ failure over time.

研究表明，纤维化的组织可能会导致器官衰竭。

14.Chronic inflammation can lead to fibrotic 纤维化的 scarring in various tissues.

慢性炎症可能导致各种组织中的纤维化的疤痕。

作文

Fibrosis is a condition that involves the thickening and scarring of connective tissue, which can lead to various health complications. One of the most concerning aspects of fibrosis is its potential to become fibrotic (纤维化的) in various organs, including the lungs, liver, and heart. The term fibrotic (纤维化的) refers specifically to the state where tissues become increasingly stiff and less functional due to the accumulation of fibrous tissue. This process can be triggered by chronic inflammation, injury, or even certain diseases, making it a significant area of study in medical research.In the lungs, for example, fibrotic (纤维化的) changes can occur as a result of conditions like idiopathic pulmonary fibrosis (IPF). IPF is a progressive disease that leads to severe breathing difficulties and reduced oxygen supply to the body. The fibrotic (纤维化的) tissue replaces normal lung tissue, resulting in a loss of elasticity and function. Patients often experience a decline in their quality of life as the disease progresses, highlighting the importance of early diagnosis and intervention.Similarly, in the liver, chronic conditions such as hepatitis or excessive alcohol consumption can lead to hepatic fibrosis. When the liver becomes fibrotic (纤维化的), it can develop into cirrhosis, which is a more severe and often irreversible condition. The fibrotic (纤维化的) tissue disrupts the normal architecture of the liver, impairing its ability to perform essential functions such as detoxification and protein synthesis. As a result, patients may face serious complications, including liver failure and increased risk of liver cancer.The heart is not immune to fibrotic (纤维化的) changes either. Conditions such as hypertension and myocardial infarction can lead to cardiac fibrosis. The fibrotic (纤维化的) tissue can interfere with the heart's electrical conduction system, leading to arrhythmias and other cardiovascular issues. Understanding how and why these fibrotic (纤维化的) changes occur is crucial for developing effective treatments to manage heart diseases.Research into fibrotic (纤维化的) diseases is ongoing, with scientists exploring various therapeutic options to halt or reverse the fibrosis process. Anti-fibrotic therapies aim to target the pathways involved in fibrosis development, potentially offering hope to patients suffering from these debilitating conditions. For instance, medications that inhibit specific growth factors responsible for collagen deposition are being studied to reduce fibrotic (纤维化的) tissue formation.In conclusion, the term fibrotic (纤维化的) encapsulates a critical aspect of many chronic diseases that can lead to significant morbidity and mortality. By understanding the mechanisms behind fibrosis and its fibrotic (纤维化的) manifestations in various organs, researchers and healthcare providers can better address the challenges posed by these conditions. Awareness and education about fibrotic (纤维化的) diseases are essential for early detection and management, ultimately improving patient outcomes and quality of life.

纤维化是一种涉及结缔组织增厚和疤痕形成的病症，可能导致各种健康并发症。纤维化最令人担忧的方面之一是它在包括肺、肝脏和心脏等各种器官中可能变得纤维化的（fibrotic）。术语纤维化的（fibrotic）专指由于纤维组织的积累而使组织变得越来越僵硬和功能下降的状态。这一过程可能由慢性炎症、损伤甚至某些疾病引发，使其成为医学研究中的一个重要研究领域。例如，在肺部，由于特发性肺纤维化（IPF）等疾病，可能发生纤维化的（fibrotic）变化。IPF是一种进行性疾病，导致严重的呼吸困难和身体氧气供应减少。纤维化的（fibrotic）组织取代正常的肺组织，导致弹性和功能的丧失。随着疾病的进展，患者的生活质量往往会下降，这突显了早期诊断和干预的重要性。同样，在肝脏中，慢性疾病如肝炎或过量饮酒可能导致肝纤维化。当肝脏变得纤维化的（fibrotic）时，可能发展为肝硬化，这是一种更为严重且通常不可逆转的状况。纤维化的（fibrotic）组织破坏了肝脏的正常结构，损害了其执行解毒和蛋白质合成等基本功能的能力。因此，患者可能面临严重的并发症，包括肝衰竭和肝癌风险增加。心脏也不免受纤维化的（fibrotic）变化的影响。高血压和心肌梗死等疾病可能导致心脏纤维化。纤维化的（fibrotic）组织可能干扰心脏的电传导系统，导致心律失常和其他心血管问题。理解这些纤维化的（fibrotic）变化如何以及为何发生，对于开发有效的治疗心脏疾病的方案至关重要。关于纤维化的（fibrotic）疾病的研究正在进行，科学家们正在探索各种治疗选择以阻止或逆转纤维化过程。抗纤维化疗法旨在针对参与纤维化发展的途径，可能为遭受这些虚弱病症的患者提供希望。例如，抑制特定生长因子的药物负责胶原蛋白沉积，正在研究以减少纤维化的（fibrotic）组织形成。总之，术语纤维化的（fibrotic）概括了许多慢性疾病的关键方面，这些疾病可能导致显著的发病率和死亡率。通过理解纤维化及其在各种器官中表现出的纤维化的（fibrotic）表现机制，研究人员和医疗提供者可以更好地应对这些病症带来的挑战。提高对纤维化的（fibrotic）疾病的认识和教育对于早期发现和管理至关重要，最终改善患者的结果和生活质量。