homeobox

简明释义

英[ˈhɒmɪəʊˌbɒks]美[ˈhoʊmioʊˌbɑːks]

n. 同源（异型）[细胞] 框

英英释义

单词用法

同义词

反义词

例句

1.Thyroid transcription factor 1(TTF-1) is a homeobox domain transcription factor of the NKX2 family.

甲状腺转录因子1是含一同源盒域的转录因子，属于NKX2家族。

2.The Arx protein(Aristaless-related homeobox) is a member of the paired class of homeoproteins.

Arx（Aristaless-relatedhomeobox）蛋白是成对同源结构域蛋白家族的一个成员。

3.Homeobox genes (Hox genes) are some highly conserved DNA sequences on the chromosomes. The protein products of Hox genes, as transcription factors, are also highly conserved.

基因是存在于染色体上的一段高度保守序列，其蛋白产物作为转录因子也是高度保守的。

4.The recent studies have revealed that some LIM homeobox genes also participate in regeneration after nerve injury and regulation of others in...

目前发现，该家族中的某些基因在成年动物及神经损伤再生过程中也可能有作用。

5.The results described here strongly suggest that, like animal homeobox genes, OSH1 plays an important role in regionalization of cell identity during early embryogenesis.

此结果也有利的表明了，OSH1同动物异型盒基因一样，在胚胎发生的早期对细胞标识的区域化起到重要作用。

6.Homeobox genes, as differentiating and regulating genes, may have effect on angiogenesis, such as HOXD3, HOXB3, HOXD10, PRX, HEX, etc.

同源异位基因作为组织分化调节基因，其与血管生成的关系已从多方面进行了研究，如HOXD3、HOXB3、HOXD10、PRX、HEX等。

7.Objective to construct eukaryotic expression vector of human pancreatic duodenal homeobox 1 (PDX-1) gene, and to detect its expression in NIH3T3 cell lines.

目的构建人胰十二指肠同源盒(PD X - 1)基因的真核表达载体，观察其在NIH3T3细胞中的表达。

8.Homeobox gene is a sort of regulatory gene which controls embryonic development and cellular differentiation.

同源框基因是一类控制胚胎发育和细胞分化的调节基因。

9.Recently, homeobox genes have been detected in vascular smooth muscle cells, and may play an important role in regulating these processes.

在此过程中，多种同源异型盒基因的表达发挥了重要的调控作用。

10.The gene containing the homeobox 同源盒 is crucial for the development of body plans in many organisms.

包含homeobox 同源盒的基因对于许多生物体的体型发育至关重要。

11.In plants, the homeobox 同源盒 genes are involved in the formation of floral structures.

在植物中，homeobox 同源盒基因参与花部结构的形成。

12.The homeobox 同源盒 proteins play a key role in regulating gene expression during embryonic development.

homeobox 同源盒蛋白在胚胎发育过程中调节基因表达中发挥了关键作用。

13.Scientists use homeobox 同源盒 sequences to trace evolutionary relationships between species.

科学家利用homeobox 同源盒序列追踪物种之间的进化关系。

14.Researchers found that mutations in the homeobox 同源盒 genes can lead to developmental disorders.

研究人员发现，homeobox 同源盒基因的突变可能导致发育障碍。

作文

The study of genetics has revealed many fascinating aspects of how organisms develop and function. One of the most intriguing discoveries in this field is the concept of the homeobox. A homeobox is a DNA sequence that encodes a protein known as a transcription factor, which plays a crucial role in regulating the expression of genes during embryonic development. This sequence is highly conserved across various species, indicating its fundamental importance in the evolutionary process. In essence, the homeobox acts like a master switch, controlling the development of specific body parts and ensuring that they form in the correct location and at the right time. For instance, in fruit flies, the homeobox genes determine the segmentation of the body and the formation of appendages. Similarly, in mammals, these genes are responsible for the development of limbs, organs, and other vital structures. The conservation of the homeobox across different species highlights the shared ancestry and common developmental pathways among diverse forms of life.Research into homeobox genes has profound implications not only for understanding basic biological processes but also for medical science. Mutations in homeobox genes can lead to developmental disorders and diseases. For example, mutations in the Hox gene cluster, a group of homeobox genes in vertebrates, can result in severe malformations, such as limb deformities or organ placement issues. By studying these genes, scientists can gain insights into the underlying mechanisms of such conditions, potentially leading to new treatments and therapies.Moreover, the role of the homeobox extends beyond mere development; it also influences regeneration and repair processes in certain organisms. Some species, like salamanders, possess remarkable regenerative abilities, allowing them to regrow limbs and other body parts. Understanding how homeobox genes facilitate these processes could inspire advancements in regenerative medicine for humans.In conclusion, the homeobox is a pivotal element in the field of genetics, serving as a key regulator of development across a wide range of organisms. Its significance in both evolutionary biology and medical research cannot be overstated. As we continue to unravel the complexities of genetic regulation, the homeobox will undoubtedly remain a focal point of investigation, offering insights that could transform our understanding of life itself and improve health outcomes for future generations.

基因学的研究揭示了生物体发育和功能的许多迷人方面。在这个领域中，一个最引人入胜的发现就是homeobox的概念。homeobox是一个DNA序列，编码一种被称为转录因子的蛋白质，这种蛋白质在胚胎发育过程中调节基因表达方面发挥着至关重要的作用。这个序列在各种物种中高度保守，表明它在进化过程中的基本重要性。从本质上讲，homeobox就像一个主开关，控制特定身体部位的发展，确保它们在正确的位置和适当的时间形成。例如，在果蝇中，homeobox基因决定身体的分段和附肢的形成。同样，在哺乳动物中，这些基因负责肢体、器官和其他重要结构的发展。homeobox在不同物种中的保守性突显了多样生命形式之间的共同祖先和共同发育途径。对homeobox基因的研究不仅对理解基本生物过程具有深远的影响，而且对医学科学也有重要意义。homeobox基因的突变可能导致发育障碍和疾病。例如，脊椎动物中一组名为Hox基因簇的homeobox基因的突变可能导致严重的畸形，如肢体畸形或器官位置问题。通过研究这些基因，科学家可以深入了解这些疾病的潜在机制，可能会导致新的治疗方法和疗法。此外，homeobox的作用不仅限于单纯的发展；它还影响某些生物体的再生和修复过程。一些物种，如蝾螈，具有显著的再生能力，能够重新生长肢体和其他身体部分。理解homeobox基因如何促进这些过程可能会激发人类再生医学的进步。总之，homeobox是基因学领域的一个关键元素，作为跨越广泛生物体发展的关键调节因子。它在进化生物学和医学研究中的重要性不容小觑。随着我们继续解开遗传调控的复杂性，homeobox无疑将继续成为研究的焦点，为我们提供可能改变我们对生命本身的理解并改善未来几代人健康结果的见解。