translocations

简明释义

英[trænsloʊˈkeɪʃənz]美[trænzloʊˈkeɪʃənz]

n. [遗]易位（translocation 的复数）

英英释义

单词用法

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例句

1.Genetic damage with DNA alterations leads to point mutations of genes, translocations of genetic material between chromosomes, and gene reduplication with amplification.

伴随DNA改变的基因损伤会导致基因的点突变、染色体间基因移位和扩增性基因复制。

2.Objective: To investigate the changes in the translocations in the skeletal muscle cell glucose transporter-4 (GLUT-4) in Wistar rats with obesity.

目的：探讨肥胖大鼠骨骼肌细胞的葡萄糖转运因子4（GLUT-4）转位变化。

3.We undertook this study to determine whether EGFR mutations, increases in EGFR copy number, or ALK translocations are present in these tumors.

我们进行此项研究，确定这类肿瘤中是否有EGFR基因的突变、EGFR基因拷贝数的增多、及ALK的易位。

4.Preimplantation genetic testing for chromosomal translocations is able to distinguish between chromosomally normal and abnormal embryos.

染色体易位植入前基因检测能够区分正常和异常染色体的胚胎。

5.Genetic damage with DNA alterations leads to point mutations of genes, translocations of genetic material between chromosomes, and gene reduplication with amplification.

伴随DNA改变的基因损伤会导致基因的点突变、染色体间基因移位和扩增性基因复制。

6.Sorting genomes by translocations plays an important role in computational biology.

有向基因组移位排序问题在计算生物学研究中占有重要位置。

7.The breakpoints of these translocations were adjacent to centromere.

易位断点靠近着丝粒。

8.Chromosome breaks may also lead to inversions and translocations.

染色体破裂也可能引起倒位与易位。

9.Conservation efforts often involve the translocations of endangered animals to safer habitats.

保护工作通常涉及将濒危动物进行迁移到更安全的栖息地。

10.The study focused on the translocations of species in response to climate change.

该研究集中于物种因气候变化而发生的迁移。

11.The translocations of certain plants can help restore damaged ecosystems.

某些植物的迁移可以帮助恢复受损的生态系统。

12.In genetics, translocations can lead to various hereditary diseases.

在遗传学中，易位可能导致各种遗传疾病。

13.The geneticist explained how translocations affect chromosome structure.

遗传学家解释了易位如何影响染色体结构。

作文

Translocations play a crucial role in various fields, including biology, genetics, and ecology. The term translocations refers to the movement of genetic material from one location to another, which can occur within a chromosome or between non-homologous chromosomes. This process can lead to significant changes in an organism's traits and is often a subject of study in evolutionary biology. Understanding translocations is essential for comprehending how species adapt to their environments and how genetic diversity is maintained within populations.In the context of genetics, translocations can result from errors during cell division, particularly during meiosis. When segments of chromosomes break and reattach to different chromosomes, it can lead to new combinations of genes. These genetic rearrangements can have profound effects on an organism's phenotype, sometimes resulting in beneficial adaptations or, conversely, harmful mutations. For example, certain cancers are associated with specific chromosomal translocations, where oncogenes are activated due to improper gene regulation.Moreover, translocations are not limited to genetic changes; they also occur in ecological contexts. In conservation biology, translocations refer to the deliberate movement of species from one habitat to another to promote population recovery or restore ecosystems. This practice has been employed to save endangered species, such as the California condor and the black-footed ferret. By relocating individuals to suitable habitats, conservationists aim to enhance genetic diversity and increase the chances of survival for these species.The success of ecological translocations depends on several factors, including the compatibility of the new environment with the species' needs, the presence of adequate resources, and the potential for human-wildlife conflict. Additionally, understanding the genetic makeup of the individuals being relocated is vital to ensure that they can adapt to their new surroundings. Failure to consider these factors can lead to unsuccessful translocations and further endanger the species involved.In summary, the concept of translocations encompasses both genetic and ecological dimensions. In genetics, translocations can drive evolution and contribute to genetic disorders, while in ecology, they represent a critical tool for conservation efforts. As our understanding of these processes deepens, we can better appreciate the complexities of life and the interconnectedness of all organisms. Through research and practical applications, the study of translocations will continue to provide insights into the mechanisms of change and adaptation in both natural and managed ecosystems.

转位在生物学、遗传学和生态学等多个领域中发挥着至关重要的作用。术语转位指的是遗传物质从一个位置移动到另一个位置，这可以发生在染色体内或非同源染色体之间。这个过程可能导致生物体特征的显著变化，并且通常是进化生物学研究的主题。理解转位对于理解物种如何适应环境以及如何在种群中维持遗传多样性是至关重要的。在遗传学的背景下，转位可能是由于细胞分裂过程中出现错误，特别是在减数分裂期间。当染色体的片段断裂并重新附着到不同的染色体上时，可能导致基因的新组合。这些遗传重排可能对生物体的表型产生深远的影响，有时会导致有益的适应，反之亦然，导致有害的突变。例如，某些癌症与特定的染色体转位有关，其中癌基因因不当的基因调控而被激活。此外，转位不仅限于遗传变化；它们也发生在生态环境中。在保护生物学中，转位指的是将物种从一个栖息地故意移动到另一个栖息地，以促进种群恢复或恢复生态系统。这一做法已被用于拯救濒危物种，如加州秃鹫和黑脚雪貂。通过将个体迁移到合适的栖息地，保护工作者旨在增强遗传多样性并提高这些物种的生存几率。生态转位的成功取决于几个因素，包括新环境与物种需求的兼容性、资源的充足性以及人类与野生动物冲突的潜在性。此外，了解被迁移个体的遗传构成对于确保它们能够适应新环境至关重要。未能考虑这些因素可能导致转位不成功，进一步危及相关物种。总之，转位的概念涵盖了遗传和生态两个维度。在遗传学中，转位可以推动进化并导致遗传疾病，而在生态学中，它们代表了保护工作的重要工具。随着我们对这些过程理解的加深，我们可以更好地欣赏生命的复杂性以及所有生物之间的相互联系。通过研究和实际应用，转位的研究将继续为我们提供关于自然和管理生态系统中变化和适应机制的见解。