mitogen

简明释义

[ˈmaɪtədʒən][ˈmaɪtədʒən]

n. [细胞] 分裂素;[细胞] 促细胞分裂剂;[细胞] 有丝分裂原

英英释义

A mitogen is a substance that stimulates or induces cell division, particularly the division of lymphocytes in the immune system.

促分裂剂是一种刺激或诱导细胞分裂的物质,尤其是免疫系统中淋巴细胞的分裂。

单词用法

mitogen activation

促分裂素激活

mitogen response

促分裂素反应

t-cell mitogen

T细胞促分裂素

b-cell mitogen

B细胞促分裂素

mitogen-induced proliferation

促分裂素诱导增殖

同义词

immunogen

免疫原

Immunogens are substances that provoke an immune response.

免疫原是引发免疫反应的物质。

lymphocyte activator

淋巴细胞激活剂

Lymphocyte activators are critical in the development of adaptive immunity.

淋巴细胞激活剂在适应性免疫的发展中至关重要。

反义词

inhibitor

抑制剂

The use of an inhibitor can help control excessive cell proliferation.

使用抑制剂可以帮助控制过度的细胞增殖。

anti-mitogenic agent

抗致增殖剂

Anti-mitogenic agents are often researched for their potential in cancer therapy.

抗致增殖剂常被研究以其在癌症治疗中的潜力。

例句

1.Mitogen activated protein (MAP) kinase, also known as extracellular signal regulated kinase, or ERK, functions in neuronal signal transduction and participates in diverse development processes.

丝裂原激活的蛋白激酶又称细胞外信号调节激酶,具有神经元信号传导功能,参与多种发育过程。

2.Aim: to explore the expression and abnormal activation of mitogen-activated protein kinase (MAPK) in the development and progression of cerebral gliomas.

目的:研究人脑胶质瘤组织中丝裂原激活蛋白激酶(MAPK)的表达及活化情况。

3.KGF is not only the mitogen of epithelial cells, but also the cytokine, which can enhance regeneration and sodium-water transport of alveolar epithelial cells.

KGF不仅是上皮细胞的丝裂原也是促进肺泡上皮细胞的钠水转运和再生的因子。

4.To investigate the expression and activation of mitogen-activated protein kinases in non-small cell lung cancer and its clinical significance.

目的:探讨丝裂原活化蛋白激酶在非小细胞肺癌中的表达及其临床意义。

5.Objective To investigate the expression changes of mitogen activated protein kinase (MAPK) in Alzheimers disease (AD) rat model.

目的:研究人脑胶质瘤组织中丝裂原激活蛋白激酶(MAPK)的表达及活化情况。

6.Mitogen activated protein (MAP) kinase, also known as extracellular signal regulated kinase, or ERK, functions in neuronal signal transduction and participates in diverse development processes.

丝裂原激活的蛋白激酶又称细胞外信号调节激酶,具有神经元信号传导功能,参与多种发育过程。

7.Objective To observe the changes in mitogen-activated protein kinase (MAPK)activity and gene expression after coronary artery balloon injury in rabbits.

目的探讨丝裂素活化蛋白激酶(MAPK)在动脉球囊损伤后内膜增殖过程中表达的变化。

8.Objective to investigate effects of PDGF on phenotypic change of glomerular mesangial cells (MC), and study intracellular mechanisms through mitogen-activated - protein kinase (MAPK) pathways.

目的研究血小板源生长因子(PDGF)对肾小球系膜细胞(MC)表型转化的影响,并探讨丝裂素活化蛋白激酶(MAPK)信号转导途径在其作用中的调控机制。

9.Results VEGF, as a mitogen specifically for endothelial cells, could strongly stimulate angiogenesis as well as vascular permeability, especially in hypoxia state.

结果VEGF是对内皮细胞特异的有丝分裂原,也有提高血管通透性的作用,在缺氧条件下作用尤为显著。

10.Researchers are exploring synthetic mitogens (促分裂因子) for potential therapeutic applications.

研究人员正在探索合成的mitogens(促分裂因子)在潜在治疗应用中的用途。

11.The scientists tested various mitogens (促分裂因子) to determine their effects on immune response.

科学家们测试了多种mitogen(促分裂因子),以确定它们对免疫反应的影响。

12.Certain plant extracts have been identified as natural mitogens (促分裂因子) that can boost immune function.

某些植物提取物已被确定为天然的mitogens(促分裂因子),可以增强免疫功能。

13.In immunology, a mitogen (促分裂因子) is often used to stimulate lymphocyte activation.

在免疫学中,mitogen(促分裂因子)通常用于刺激淋巴细胞活化。

14.The research indicated that the presence of a specific mitogen (促分裂因子) can significantly enhance cell proliferation.

研究表明,特定的mitogen(促分裂因子)的存在可以显著增强细胞增殖。

作文

In the realm of immunology and cellular biology, the term mitogen refers to a substance that stimulates cell division and proliferation. These substances play a crucial role in the immune response by promoting the growth and activation of lymphocytes, which are essential for the body’s defense mechanisms against pathogens. Understanding the function and significance of mitogens can provide insights into various biological processes and potential therapeutic applications.One of the most well-known examples of a mitogen is phytohemagglutinin (PHA), a lectin derived from red kidney beans. PHA is commonly used in laboratory settings to stimulate T-cell proliferation in vitro. When lymphocytes are exposed to PHA, they undergo a series of changes that lead to their activation and division. This process is vital for researchers studying immune responses, as it allows them to analyze how cells react to different stimuli and how they can be manipulated for therapeutic purposes.Moreover, mitogens are not limited to plant-derived substances. Various viruses and bacterial components also exhibit mitogenic properties. For instance, certain viral proteins can trigger lymphocyte activation, leading to an enhanced immune response. This characteristic is particularly important in vaccine development, as it can help researchers design vaccines that effectively stimulate the immune system.In addition to their role in normal immune function, mitogens have been implicated in various diseases, including cancer. Tumor cells often exploit mitogenic pathways to promote their own growth and survival. By understanding how mitogens influence cell behavior, scientists can develop targeted therapies that inhibit these pathways, potentially leading to more effective cancer treatments.Furthermore, the study of mitogens extends beyond basic research. Clinically, measuring the response of lymphocytes to mitogens can serve as a diagnostic tool. For example, in immunodeficiency disorders, the ability of lymphocytes to respond to mitogens may be impaired, indicating a compromised immune system. Therefore, assessing the mitogenic response can provide valuable information about a patient’s immune status and guide treatment decisions.In conclusion, mitogens are vital substances that drive cell division and play a significant role in the immune response. Their ability to stimulate lymphocyte proliferation has made them important tools in both research and clinical settings. As we continue to explore the complexities of the immune system, the study of mitogens will undoubtedly yield new insights into health and disease. By harnessing the power of these substances, we can pave the way for innovative therapies and improve our understanding of cellular dynamics in various biological contexts.

在免疫学和细胞生物学领域,术语mitogen指的是一种刺激细胞分裂和增殖的物质。这些物质在免疫反应中发挥着至关重要的作用,促进淋巴细胞的生长和激活,而淋巴细胞对于身体抵御病原体的防御机制是必不可少的。理解mitogens的功能和重要性可以为各种生物过程和潜在的治疗应用提供见解。其中一个最著名的mitogen例子是从红腰豆中提取的凝集素植物血凝素(PHA)。PHA通常在实验室环境中用于刺激体外T细胞增殖。当淋巴细胞暴露于PHA时,它们会经历一系列变化,从而导致它们的激活和分裂。这个过程对研究人员研究免疫反应至关重要,因为它使他们能够分析细胞如何对不同刺激做出反应,以及如何操控这些反应以用于治疗目的。此外,mitogens并不仅限于植物衍生物。各种病毒和细菌成分也表现出促分裂特性。例如,某些病毒蛋白可以触发淋巴细胞激活,从而增强免疫反应。这一特性在疫苗开发中尤为重要,因为它可以帮助研究人员设计有效刺激免疫系统的疫苗。除了在正常免疫功能中的作用外,mitogens还与多种疾病相关,包括癌症。肿瘤细胞通常利用促分裂途径来促进自身的生长和存活。通过理解mitogens如何影响细胞行为,科学家可以开发靶向疗法,抑制这些途径,从而可能导致更有效的癌症治疗。此外,对mitogens的研究超越了基础研究。在临床上,测量淋巴细胞对mitogens的反应可以作为一种诊断工具。例如,在免疫缺陷疾病中,淋巴细胞对mitogens的反应能力可能受到损害,这表明免疫系统受到损害。因此,评估促分裂反应可以提供有关患者免疫状态的宝贵信息,并指导治疗决策。总之,mitogens是驱动细胞分裂的重要物质,在免疫反应中发挥着重要作用。它们刺激淋巴细胞增殖的能力使它们成为研究和临床环境中的重要工具。随着我们继续探索免疫系统的复杂性,对mitogens的研究无疑将为健康和疾病提供新的见解。通过利用这些物质的力量,我们可以为创新疗法铺平道路,改善我们对各种生物背景下细胞动态的理解。