diamine oxidase

简明释义

二胺氧化酶

英英释义

例句

1.Foods high in histamine may require higher levels of diamine oxidase to be properly metabolized.

富含组胺的食物可能需要更高水平的二胺氧化酶才能被正确代谢。

2.The enzyme diamine oxidase is crucial for breaking down histamine in the body.

酶二胺氧化酶对分解体内的组胺至关重要。

3.A deficiency in diamine oxidase can lead to increased histamine levels, causing allergic reactions.

缺乏二胺氧化酶可能导致组胺水平升高，从而引发过敏反应。

4.Researchers are studying the role of diamine oxidase in gastrointestinal disorders.

研究人员正在研究二胺氧化酶在胃肠道疾病中的作用。

5.Patients with histamine intolerance often have low activity of diamine oxidase.

患有组胺不耐症的患者通常二胺氧化酶活性较低。

作文

Diamine oxidase (DAO) is an enzyme that plays a crucial role in the metabolism of biogenic amines, which are organic compounds that contain one or more amine groups. These compounds are naturally occurring in the body and can have significant effects on various physiological functions. The primary function of diamine oxidase (二胺氧化酶) is to catalyze the oxidative deamination of diamines, such as histamine and putrescine, converting them into their corresponding aldehydes. This process is essential for maintaining the balance of amines in the body, as excess levels can lead to various health issues.The importance of diamine oxidase (二胺氧化酶) can be observed in several areas of health and medicine. For instance, elevated levels of histamine in the body can result in allergic reactions and other histamine-related disorders. DAO helps regulate these levels by breaking down histamine, thus preventing its accumulation. Individuals with a deficiency in diamine oxidase (二胺氧化酶) may experience symptoms such as headaches, digestive issues, and skin reactions due to the inability to effectively metabolize histamine.Moreover, research has shown that diamine oxidase (二胺氧化酶) may play a role in gastrointestinal health. It is present in the intestinal mucosa and is involved in the breakdown of dietary amines that are absorbed during digestion. A healthy level of DAO is necessary for proper digestion and absorption of nutrients. When the activity of diamine oxidase (二胺氧化酶) is compromised, it can lead to conditions like food intolerance and irritable bowel syndrome (IBS).In addition to its metabolic functions, diamine oxidase (二胺氧化酶) has also been studied for its potential therapeutic applications. Some studies suggest that supplementing with DAO may help individuals with histamine intolerance manage their symptoms more effectively. By increasing the levels of this enzyme, patients may experience relief from symptoms associated with high histamine levels, such as migraines, hives, and gastrointestinal discomfort.Furthermore, the role of diamine oxidase (二胺氧化酶) extends beyond just histamine metabolism. It is also involved in the regulation of other biogenic amines, including tyramine and cadaverine, which can influence mood and cognitive function. This highlights the broader implications of DAO in neurobiology and mental health, suggesting that maintaining optimal levels of this enzyme could be beneficial for mental well-being.In conclusion, diamine oxidase (二胺氧化酶) is a vital enzyme that significantly impacts our health by regulating the levels of biogenic amines in the body. Its functions extend across various physiological systems, including digestion, immune response, and even mental health. Understanding the role of diamine oxidase (二胺氧化酶) not only enhances our knowledge of human physiology but also opens up avenues for potential treatments for related disorders. As research continues, the significance of this enzyme in both health and disease will likely become even more apparent, emphasizing the need for further exploration in this fascinating area of biochemistry.

二胺氧化酶（DAO）是一种在生物胺代谢中发挥关键作用的酶，这些生物胺是含有一个或多个胺基团的有机化合物。它们在体内自然存在，并对各种生理功能具有重要影响。二胺氧化酶的主要功能是催化二胺的氧化脱氨反应，例如组胺和腐胺，将其转化为相应的醛。这一过程对于维持体内胺的平衡至关重要，因为过量的胺可能导致各种健康问题。二胺氧化酶的重要性可以在健康和医学的多个领域观察到。例如，体内组胺水平升高可能导致过敏反应和其他与组胺相关的疾病。DAO通过分解组胺来帮助调节这些水平，从而防止其积累。缺乏二胺氧化酶的人可能会由于无法有效代谢组胺而出现头痛、消化问题和皮肤反应等症状。此外，研究表明，二胺氧化酶可能在胃肠健康中发挥作用。它存在于肠粘膜中，并参与分解在消化过程中吸收的膳食胺。保持适当的DAO水平对于正确的消化和营养吸收是必要的。当二胺氧化酶的活性受到损害时，可能会导致食物不耐受和肠易激综合症（IBS）等疾病。除了代谢功能外，二胺氧化酶还被研究其潜在的治疗应用。一些研究表明，补充DAO可能帮助组胺不耐受患者更有效地管理他们的症状。通过增加这种酶的水平，患者可能会体验到与高组胺水平相关的症状缓解，如偏头痛、荨麻疹和胃肠不适。此外，二胺氧化酶的作用不仅限于组胺代谢。它还参与调节其他生物胺，包括酪胺和尸胺，这些生物胺可能影响情绪和认知功能。这突显了DAO在神经生物学和心理健康中的更广泛意义，表明维持这种酶的最佳水平可能对心理健康有益。总之，二胺氧化酶是一种重要的酶，通过调节体内生物胺的水平显著影响我们的健康。它的功能跨越消化、免疫反应甚至心理健康等多个生理系统。理解二胺氧化酶的作用不仅增强了我们对人体生理学的认识，还为相关疾病的潜在治疗开辟了途径。随着研究的继续，这种酶在健康和疾病中的重要性可能会变得更加明显，强调了在这个迷人的生物化学领域进一步探索的必要性。