aminosalicylic acid

简明释义

氨基水杨酸

英英释义

例句

1.It is important to take aminosalicylic acid as directed by your healthcare provider.

按照医疗提供者的指示服用氨基水杨酸是很重要的。

2.The doctor prescribed aminosalicylic acid for the treatment of tuberculosis.

医生开了氨基水杨酸用于治疗结核病。

3.Patients taking aminosalicylic acid should be monitored for side effects.

服用氨基水杨酸的患者应当监测副作用。

4.Research indicates that aminosalicylic acid can enhance the effectiveness of certain antibiotics.

研究表明，氨基水杨酸可以增强某些抗生素的效果。

5.The formulation of aminosalicylic acid is available in both tablet and powder form.

氨基水杨酸的制剂有片剂和粉剂两种形式。

作文

Aminosalicylic acid, often abbreviated as PAS, is a medication that has been used primarily in the treatment of tuberculosis (TB). It is an important part of the arsenal against this infectious disease, especially in cases where the bacteria have developed resistance to other antibiotics. The chemical structure of aminosalicylic acid (氨基水杨酸) allows it to inhibit the growth of Mycobacterium tuberculosis, the bacterium responsible for TB. This compound was first introduced in the mid-20th century and has since played a crucial role in TB therapy.The mechanism of action of aminosalicylic acid (氨基水杨酸) is quite fascinating. It acts as a competitive inhibitor of para-aminobenzoic acid (PABA), which is essential for the synthesis of folate in bacteria. By blocking the utilization of PABA, aminosalicylic acid (氨基水杨酸) effectively starves the bacteria of the nutrients necessary for their growth and reproduction. This makes it a valuable addition to multi-drug regimens used to treat TB, particularly in resistant strains where traditional treatments may fail.In clinical practice, aminosalicylic acid (氨基水杨酸) is usually administered in combination with other anti-tubercular drugs such as isoniazid, rifampicin, and ethambutol. This combination therapy not only enhances the effectiveness of treatment but also helps prevent the development of further drug resistance. Patients are typically prescribed aminosalicylic acid (氨基水杨酸) for several months, depending on the severity of their condition and the specific strain of TB they are infected with.Despite its effectiveness, the use of aminosalicylic acid (氨基水杨酸) is not without challenges. Some patients may experience side effects such as gastrointestinal disturbances, allergic reactions, or liver toxicity. Therefore, healthcare providers must monitor patients closely during treatment to manage any adverse effects that may arise. Additionally, the availability of aminosalicylic acid (氨基水杨酸) can be limited in certain regions, particularly in low-income countries where TB is most prevalent.In conclusion, aminosalicylic acid (氨基水杨酸) remains a vital component in the fight against tuberculosis. Its ability to combat resistant strains of TB highlights the importance of ongoing research and development in the field of infectious diseases. As we continue to face challenges posed by antibiotic resistance, medications like aminosalicylic acid (氨基水杨酸) will be crucial in ensuring effective treatment options for patients worldwide. Understanding the role of such compounds not only enriches our knowledge of pharmacology but also underscores the significance of comprehensive approaches to global health issues.

氨基水杨酸，通常缩写为PAS，是一种主要用于治疗结核病（TB）的药物。它是对抗这种传染病的重要武器，特别是在细菌对其他抗生素产生耐药性时。aminosalicylic acid（氨基水杨酸）的化学结构使其能够抑制引起结核病的分枝杆菌的生长。这种化合物在20世纪中叶首次被引入，并在结核病治疗中发挥了至关重要的作用。aminosalicylic acid（氨基水杨酸）的作用机制非常有趣。它作为对氨基苯甲酸（PABA）的竞争性抑制剂，PABA是细菌合成叶酸所必需的。通过阻止PABA的利用，aminosalicylic acid（氨基水杨酸）有效地剥夺了细菌生长和繁殖所需的营养。这使得它成为治疗结核病多药联合方案中的宝贵补充，特别是在传统治疗可能失败的耐药菌株中。在临床实践中，aminosalicylic acid（氨基水杨酸）通常与其他抗结核药物如异烟肼、利福平和乙胺丁醇联合使用。这种联合治疗不仅增强了治疗效果，还帮助防止进一步的耐药性发展。患者通常会根据他们的病情严重程度和感染的特定结核菌株，接受几个月的aminosalicylic acid（氨基水杨酸)治疗。尽管有效，但使用aminosalicylic acid（氨基水杨酸）并非没有挑战。一些患者可能会经历副作用，如胃肠道不适、过敏反应或肝毒性。因此，医疗提供者必须在治疗期间密切监测患者，以管理可能出现的任何不良反应。此外，aminosalicylic acid（氨基水杨酸）在某些地区的可获得性可能有限，特别是在结核病最为流行的低收入国家。总之，aminosalicylic acid（氨基水杨酸）仍然是抗击结核病的重要组成部分。它对抗耐药性结核菌株的能力突显了在传染病领域持续研究和发展的重要性。随着我们继续面临抗生素耐药性带来的挑战，像aminosalicylic acid（氨基水杨酸）这样的药物将在确保全球患者有效治疗选择方面至关重要。理解这些化合物的作用不仅丰富了我们对药理学的认识，也强调了对全球健康问题采取全面方法的重要性。