aminocaproic acid
简明释义
氨基己酸
英英释义
Aminocaproic acid is a synthetic amino acid that acts as an antifibrinolytic agent, which means it helps to prevent the breakdown of fibrin in blood clots. | 氨基己酸是一种合成氨基酸,作为抗纤溶药物,可以帮助防止血块中的纤维蛋白分解。 |
例句
1.Before the operation, the anesthesiologist recommended aminocaproic acid to minimize bleeding risks.
在手术前,麻醉师建议使用氨基己酸以降低出血风险。
2.The doctor prescribed aminocaproic acid for the patient's excessive bleeding after surgery.
医生为患者手术后的过度出血开了氨基己酸。
3.In cases of trauma, aminocaproic acid can help reduce blood loss.
在创伤情况下,氨基己酸可以帮助减少失血。
4.The use of aminocaproic acid is common in dental procedures to control bleeding.
在牙科手术中,常用氨基己酸来控制出血。
5.Patients with hemophilia may benefit from aminocaproic acid treatment during bleeding episodes.
患有血友病的患者在出血发作时可能会受益于氨基己酸治疗。
作文
Aminocaproic acid, known scientifically as a synthetic lysine analog, plays a significant role in the field of medicine, particularly in the management of bleeding disorders. This compound, which is a type of antifibrinolytic agent, works by inhibiting the activation of plasminogen to plasmin, thereby preventing the breakdown of fibrin and promoting clot stability. Its clinical applications are diverse, ranging from surgical procedures to treatment of conditions like hemophilia and excessive bleeding due to trauma.The mechanism of action of aminocaproic acid is crucial for its effectiveness. By binding to the lysine-binding sites on plasminogen, it prevents the conversion of plasminogen into plasmin. Plasmin is an enzyme responsible for breaking down fibrin, the protein that forms the mesh structure of blood clots. Thus, by inhibiting this process, aminocaproic acid helps maintain hemostasis during surgeries or after traumatic injuries where blood loss is a concern.In surgical settings, especially in procedures that have a high risk of bleeding, such as cardiac surgery or orthopedic operations, the administration of aminocaproic acid can significantly reduce the need for blood transfusions. This is not only beneficial for the patient’s recovery but also helps in conserving blood resources, which is essential in modern medical practice.Moreover, aminocaproic acid has been studied for its effectiveness in treating other conditions. For instance, patients suffering from severe menstrual bleeding or those with liver cirrhosis often benefit from its use. The ability of aminocaproic acid to stabilize clots can lead to improved outcomes and quality of life for these patients.Despite its benefits, it is important to be aware of the potential side effects associated with aminocaproic acid. Some patients may experience gastrointestinal disturbances, such as nausea or diarrhea. More serious complications, although rare, can include thrombosis, as excessive clotting can occur if aminocaproic acid is not used judiciously. Therefore, careful monitoring during treatment is essential to ensure patient safety.In conclusion, aminocaproic acid is a valuable tool in the management of bleeding disorders and surgical procedures. Its ability to inhibit fibrinolysis makes it a critical agent in maintaining hemostasis and reducing the risks associated with excessive bleeding. As with any medication, it is vital for healthcare providers to weigh the benefits against the potential risks when considering the use of aminocaproic acid. Ongoing research continues to explore new applications and optimize its use in clinical settings, ensuring that patients receive the best possible care while minimizing complications.
氨基己酸,科学上被称为合成赖氨酸类似物,在医学领域中扮演着重要角色,特别是在出血性疾病的管理中。该化合物是一种抗纤溶剂,通过抑制纤溶酶原转化为纤溶酶的激活,从而防止纤维蛋白的降解并促进血块的稳定性。它的临床应用广泛,涵盖了从外科手术到治疗如血友病和因创伤引起的过度出血等情况。氨基己酸的作用机制对于其有效性至关重要。通过与纤溶酶原上的赖氨酸结合位点结合,它阻止了纤溶酶原转化为纤溶酶的过程。纤溶酶是一种负责分解纤维蛋白的酶,而纤维蛋白是形成血块网状结构的蛋白质。因此,通过抑制这一过程,氨基己酸有助于在手术或创伤后保持止血。在外科手术中,尤其是在具有高出血风险的手术中,例如心脏手术或骨科手术,给予氨基己酸可以显著减少输血的需求。这不仅有利于患者的恢复,还有助于节约血液资源,这在现代医学实践中至关重要。此外,氨基己酸还被研究用于治疗其他疾病。例如,严重月经出血或肝硬化患者通常会受益于其使用。氨基己酸稳定血块的能力可以改善这些患者的结果和生活质量。尽管有其好处,但需要注意与氨基己酸相关的潜在副作用。一些患者可能会经历胃肠道不适,如恶心或腹泻。更严重的并发症虽然罕见,但可能包括血栓形成,因为如果不谨慎使用氨基己酸,可能会发生过度凝血。因此,在治疗过程中仔细监测非常重要,以确保患者安全。总之,氨基己酸是出血疾病和外科手术管理中的一种宝贵工具。其抑制纤溶的能力使其成为维持止血和减少与过度出血相关风险的关键药物。与任何药物一样,医疗提供者在考虑使用氨基己酸时,必须权衡其益处与潜在风险。持续的研究继续探索新的应用并优化其在临床中的使用,确保患者在最小化并发症的同时获得最佳护理。
相关单词