amino acid sequence

简明释义

氨基酸顺序

英英释义

例句

1.By comparing the amino acid sequence 氨基酸序列 of different species, scientists can trace evolutionary relationships.

通过比较不同物种的氨基酸序列，科学家可以追踪进化关系。

2.Mutations in the amino acid sequence 氨基酸序列 can lead to genetic disorders.

在氨基酸序列中的突变可能导致遗传疾病。

3.The amino acid sequence 氨基酸序列 is crucial for designing effective vaccines.

设计有效疫苗时，氨基酸序列至关重要。

4.Researchers are analyzing the amino acid sequence 氨基酸序列 to understand the disease mechanism.

研究人员正在分析氨基酸序列以了解疾病机制。

5.The amino acid sequence 氨基酸序列 of the protein determines its function.

蛋白质的氨基酸序列决定了它的功能。

作文

The study of biology often leads us to explore the intricate details of life at the molecular level. One of the most fascinating aspects of this field is the role that proteins play in living organisms. Proteins are essential macromolecules that perform a vast array of functions, from catalyzing biochemical reactions to providing structural support in cells. At the heart of protein biology lies the concept of the amino acid sequence, which is crucial for understanding how proteins are formed and how they function.The amino acid sequence refers to the specific order of amino acids in a protein. Amino acids are the building blocks of proteins, and there are 20 different standard amino acids that can be combined in various sequences to create countless proteins. The sequence of these amino acids determines the protein's structure and, consequently, its function. For instance, a slight alteration in the amino acid sequence can lead to significant changes in the protein's properties and its ability to perform its biological role.To illustrate the importance of the amino acid sequence, consider the case of hemoglobin, the protein responsible for transporting oxygen in our blood. Hemoglobin is made up of four polypeptide chains, each with a unique amino acid sequence. If just one amino acid in this sequence is changed due to a mutation, it can lead to disorders such as sickle cell anemia. This condition arises when a single nucleotide change results in the substitution of valine for glutamic acid in the amino acid sequence of hemoglobin, causing the red blood cells to deform into a sickle shape, which impairs their ability to carry oxygen effectively.Moreover, understanding the amino acid sequence of proteins is vital for biotechnological applications and drug development. Scientists can design drugs that specifically target proteins by analyzing their amino acid sequence. For example, monoclonal antibodies, which are used in cancer therapy, are developed by identifying specific proteins on the surface of cancer cells. By targeting these proteins, researchers can create treatments that effectively inhibit tumor growth.In addition to its applications in medicine, the amino acid sequence is also essential in the field of bioinformatics, where computational tools are used to analyze and predict protein structures based on their sequences. The advent of high-throughput sequencing technologies has allowed scientists to determine the amino acid sequences of thousands of proteins rapidly. These advancements have opened new avenues for research, enabling scientists to investigate the relationships between different proteins and their functions within the cell.In conclusion, the amino acid sequence is a fundamental concept in biology that underpins our understanding of protein structure and function. It is essential not only for the basic science of life but also for practical applications in medicine and biotechnology. As we continue to unravel the complexities of life at the molecular level, the significance of the amino acid sequence will undoubtedly remain a central focus of scientific inquiry, leading to discoveries that could transform our understanding of health and disease.

生物学的研究常常使我们深入探索生命在分子层面的复杂细节。这个领域最迷人的方面之一是蛋白质在生物体中的作用。蛋白质是必不可少的大分子，执行着各种各样的功能，从催化生化反应到为细胞提供结构支持。在蛋白质生物学的核心概念中，有一个至关重要的概念，即氨基酸序列，它对于理解蛋白质是如何形成及其功能至关重要。氨基酸序列是指蛋白质中氨基酸的特定顺序。氨基酸是蛋白质的构建块，有20种不同的标准氨基酸可以以各种序列组合形成无数的蛋白质。这些氨基酸的顺序决定了蛋白质的结构，因此也决定了其功能。例如，氨基酸序列的微小改变可能导致蛋白质性质的显著变化以及其执行生物学角色的能力。为了说明氨基酸序列的重要性，考虑血红蛋白的案例，血红蛋白是负责运输氧气的蛋白质。血红蛋白由四条多肽链组成，每条链都有独特的氨基酸序列。如果由于突变而改变了这个序列中的一个氨基酸，就可能导致如镰刀型细胞贫血等疾病的发生。这种情况发生在一个核苷酸的变化导致在血红蛋白的氨基酸序列中用缬氨酸替代了谷氨酸，从而使红细胞变形为镰刀形状，影响了它们有效运输氧气的能力。此外，理解蛋白质的氨基酸序列对生物技术应用和药物开发至关重要。科学家们可以通过分析蛋白质的氨基酸序列来设计专门针对特定蛋白质的药物。例如，单克隆抗体用于癌症治疗，是通过识别癌细胞表面的特定蛋白质而开发的。通过靶向这些蛋白质，研究人员可以创建有效抑制肿瘤生长的治疗方法。除了在医学上的应用，氨基酸序列在生物信息学领域也至关重要，计算工具被用来分析和预测基于序列的蛋白质结构。高通量测序技术的出现使科学家能够快速确定成千上万种蛋白质的氨基酸序列。这些进展为研究开辟了新的途径，使科学家能够调查不同蛋白质之间的关系及其在细胞内的功能。总之，氨基酸序列是生物学中的一个基本概念，它支撑着我们对蛋白质结构和功能的理解。它不仅对生命的基础科学至关重要，而且对医学和生物技术的实际应用也至关重要。随着我们继续揭开生命在分子层面的复杂性，氨基酸序列的重要性无疑将继续成为科学探究的中心焦点，带来可能改变我们对健康和疾病理解的发现。