amine oxidase

简明释义

胺氧化酶

英英释义

例句

1.Certain medications target amine oxidase to alleviate symptoms of depression.

某些药物以胺氧化酶为目标，以缓解抑郁症状。

2.The activity of amine oxidase can vary significantly between individuals.

个体之间的胺氧化酶活性可能有显著差异。

3.Researchers found that amine oxidase plays a role in regulating blood pressure.

研究人员发现胺氧化酶在调节血压方面起着作用。

4.The enzyme amine oxidase is crucial for the metabolism of neurotransmitters.

酶胺氧化酶对神经递质的代谢至关重要。

5.Inhibition of amine oxidase can lead to increased levels of certain biogenic amines.

抑制胺氧化酶可能导致某些生物胺水平升高。

作文

Amine oxidases are a group of enzymes that play a crucial role in the metabolism of amines, which are organic compounds derived from ammonia. These enzymes catalyze the oxidative deamination of monoamines and polyamines, leading to the production of aldehydes, hydrogen peroxide, and ammonia. Understanding the function and significance of amine oxidase (胺氧化酶) is essential for several reasons, particularly in the fields of biochemistry and pharmacology.Firstly, amine oxidase (胺氧化酶) is involved in the regulation of neurotransmitters in the brain. Neurotransmitters such as dopamine, norepinephrine, and serotonin are vital for mood regulation, cognition, and overall mental health. The activity of amine oxidase (胺氧化酶) helps to break down these neurotransmitters after they have fulfilled their purpose, thus preventing excessive accumulation and ensuring proper signaling within the nervous system. This regulatory mechanism highlights the importance of amine oxidase (胺氧化酶) in maintaining mental health and preventing disorders such as depression and anxiety.Secondly, amine oxidase (胺氧化酶) has significant implications in drug metabolism. Many pharmaceuticals are designed to target specific receptors or pathways in the body, and their effectiveness can be influenced by how they are metabolized. In particular, the enzyme known as monoamine oxidase (MAO) is a type of amine oxidase (胺氧化酶) that breaks down monoamines. Inhibition of MAO can enhance the effects of certain antidepressants, making it a target for drug development. Understanding the interactions between drugs and amine oxidase (胺氧化酶) can lead to more effective treatments for various conditions.Moreover, amine oxidase (胺氧化酶) is also relevant in the context of cardiovascular health. The enzyme is involved in the metabolism of biogenic amines, which can influence blood pressure and heart function. For instance, the breakdown of norepinephrine by amine oxidase (胺氧化酶) can affect vascular tone and cardiac output. Research has shown that dysregulation of amine oxidase (胺氧化酶) activity may contribute to cardiovascular diseases, making it an important area of study for understanding heart health.Additionally, amine oxidase (胺氧化酶) is involved in the immune response. Certain types of amine oxidase (胺氧化酶) are expressed in immune cells and can modulate inflammation. By regulating the levels of amines in the body, these enzymes can influence the activation and proliferation of immune cells, thereby playing a role in the body's defense mechanisms against pathogens.In conclusion, the study of amine oxidase (胺氧化酶) is vital for understanding various physiological processes and their implications for health and disease. From its role in neurotransmitter metabolism to its impact on cardiovascular health and immune function, amine oxidase (胺氧化酶) serves as a key player in numerous biochemical pathways. Continued research in this area may lead to new therapeutic strategies and a deeper understanding of human biology.

胺氧化酶是一组在胺类物质代谢中发挥重要作用的酶。这些酶催化单胺和多胺的氧化脱氨反应，导致醛、过氧化氢和氨的产生。理解胺氧化酶（amine oxidase）的功能和重要性对于生物化学和药理学等多个领域至关重要。首先，胺氧化酶（amine oxidase）参与大脑中神经递质的调节。多巴胺、去甲肾上腺素和血清素等神经递质对情绪调节、认知和整体心理健康至关重要。胺氧化酶（amine oxidase）的活性有助于在神经递质完成其功能后将其分解，从而防止过量积累，确保神经系统内的适当信号传递。这一调节机制突显了胺氧化酶（amine oxidase）在维持心理健康和预防抑郁症和焦虑症等障碍中的重要性。其次，胺氧化酶（amine oxidase）在药物代谢中具有重要意义。许多药物旨在靶向体内特定受体或通路，其有效性可能受到它们如何被代谢的影响。特别是，单胺氧化酶（MAO）是一种类型的胺氧化酶（amine oxidase），负责分解单胺。抑制MAO可以增强某些抗抑郁药的效果，使其成为药物开发的目标。理解药物与胺氧化酶（amine oxidase）之间的相互作用可以导致更有效的各种疾病治疗。此外，胺氧化酶（amine oxidase）在心血管健康方面也相关。该酶参与生物胺的代谢，这可能影响血压和心脏功能。例如，胺氧化酶（amine oxidase）对去甲肾上腺素的分解可能影响血管张力和心输出量。研究表明，胺氧化酶（amine oxidase）活性的失调可能导致心血管疾病，因此这是理解心脏健康的重要研究领域。此外，胺氧化酶（amine oxidase）还参与免疫反应。某些类型的胺氧化酶（amine oxidase）在免疫细胞中表达，可以调节炎症。通过调节体内胺类物质的水平，这些酶可以影响免疫细胞的激活和增殖，从而在机体对抗病原体的防御机制中发挥作用。总之，研究胺氧化酶（amine oxidase）对于理解各种生理过程及其对健康和疾病的影响至关重要。从其在神经递质代谢中的作用到对心血管健康和免疫功能的影响，胺氧化酶（amine oxidase）在众多生化通路中充当关键角色。在这一领域的持续研究可能会导致新的治疗策略和对人类生物学的更深入理解。