alcohol dehydrogenase

简明释义

醇脱氢酶

英英释义

例句

1.Researchers are studying how alcohol dehydrogenase affects alcohol tolerance in different populations.

研究人员正在研究醇脱氢酶如何影响不同人群的酒精耐受性。

2.Inhibitors of alcohol dehydrogenase are being developed to help treat alcohol use disorders.

针对醇脱氢酶的抑制剂正在开发，以帮助治疗酒精使用障碍。

3.High levels of alcohol dehydrogenase can lead to faster alcohol metabolism in some individuals.

高水平的醇脱氢酶可能导致某些个体更快地代谢酒精。

4.The enzyme alcohol dehydrogenase plays a crucial role in the metabolism of ethanol.

酶醇脱氢酶在乙醇的代谢中起着至关重要的作用。

5.The activity of alcohol dehydrogenase can vary significantly among individuals due to genetic factors.

由于遗传因素，个体之间的醇脱氢酶活性可能有显著差异。

作文

Alcohol is a substance that has been consumed by humans for centuries, often in social settings, celebrations, and various cultural practices. However, the metabolism of alcohol in the human body is a complex process that involves several enzymes, one of the most important being alcohol dehydrogenase. This enzyme plays a crucial role in breaking down ethanol, the type of alcohol found in beverages, into acetaldehyde, which is then further metabolized to less harmful substances. Understanding the function and significance of alcohol dehydrogenase can provide insights into how our bodies handle alcohol consumption and the potential health implications associated with it.Alcohol dehydrogenase is predominantly found in the liver, where it facilitates the first step of alcohol metabolism. When a person consumes alcoholic beverages, the ethanol enters the bloodstream and is transported to the liver. Here, alcohol dehydrogenase catalyzes the conversion of ethanol into acetaldehyde, a toxic compound that can lead to various health issues if accumulated in the body. The rate at which this enzyme works can vary significantly among individuals due to genetic factors, age, sex, and even dietary habits.The activity of alcohol dehydrogenase is influenced by genetic polymorphisms, which are variations in the DNA sequence that can affect enzyme efficiency. Some individuals possess a more active form of this enzyme, allowing them to metabolize alcohol more quickly than others. Consequently, these individuals may experience different effects from alcohol consumption, including tolerance or susceptibility to alcohol-related diseases. For instance, those with lower levels of alcohol dehydrogenase may be more prone to hangovers and other negative effects after drinking.In addition to genetic factors, the amount of alcohol dehydrogenase present in the liver can also be affected by regular alcohol consumption. Chronic drinkers may experience an increase in the production of this enzyme, leading to a higher tolerance for alcohol over time. However, this adaptation can also have detrimental effects on health, as the body may become more reliant on alcohol, increasing the risk of developing alcohol use disorders.Moreover, understanding the role of alcohol dehydrogenase extends beyond just individual metabolism. It has significant implications for public health, particularly concerning alcohol-related accidents and long-term health consequences such as liver disease and certain types of cancer. By studying this enzyme, researchers aim to develop strategies to mitigate the risks associated with excessive alcohol consumption, including educational programs and potential pharmacological interventions.In conclusion, alcohol dehydrogenase is a vital enzyme in the metabolism of alcohol, influencing how our bodies process ethanol and its byproducts. Its varying activity among individuals highlights the complexity of alcohol metabolism and its health impacts. As society continues to grapple with the challenges posed by alcohol consumption, a deeper understanding of alcohol dehydrogenase can inform both personal choices and public health policies aimed at reducing the risks associated with alcohol use.

酒精是一种人类消费了几个世纪的物质，常常出现在社交场合、庆祝活动和各种文化实践中。然而，酒精在人体内的代谢是一个复杂的过程，涉及多种酶，其中最重要的之一就是酒精脱氢酶。该酶在将饮料中的乙醇分解为乙醛的过程中发挥着关键作用，随后乙醛又被进一步代谢为更无害的物质。理解酒精脱氢酶的功能和重要性可以提供关于我们身体如何处理酒精消费及其潜在健康影响的见解。酒精脱氢酶主要存在于肝脏中，在酒精代谢的第一步中起着催化作用。当一个人消费含酒精的饮料时，乙醇进入血液并被运输到肝脏。在这里，酒精脱氢酶催化乙醇转化为乙醛，这是一种有毒化合物，如果在体内积累可能导致各种健康问题。该酶的工作速率因个体而异，受遗传因素、年龄、性别甚至饮食习惯的影响。酒精脱氢酶的活性受基因多态性的影响，即DNA序列中的变异，这可能影响酶的效率。一些个体拥有更活跃的这种酶，使他们能够比其他人更快地代谢酒精。因此，这些个体可能会经历不同的酒精消费效果，包括耐受性或对酒精相关疾病的易感性。例如，低水平的酒精脱氢酶的人可能在饮酒后更容易出现宿醉和其他负面影响。除了遗传因素，肝脏中酒精脱氢酶的数量也可能受到规律性饮酒的影响。慢性饮酒者可能会经历这种酶的产生增加，从而导致随着时间的推移对酒精的耐受性提高。然而，这种适应也可能对健康产生不利影响，因为身体可能对酒精变得更加依赖，从而增加发展酒精使用障碍的风险。此外，理解酒精脱氢酶的作用不仅限于个体代谢。它对公共健康具有重要意义，特别是涉及酒精相关事故和长期健康后果，如肝病和某些类型的癌症。通过研究这种酶，研究人员旨在制定策略，以减轻与过度饮酒相关的风险，包括教育项目和潜在的药物干预。总之，酒精脱氢酶是酒精代谢中的一种重要酶，影响我们身体如何处理乙醇及其副产品。其在个体之间的变化活动突显了酒精代谢的复杂性及其健康影响。随着社会继续应对酒精消费带来的挑战，对酒精脱氢酶的更深入理解可以为减少与酒精使用相关的风险的个人选择和公共卫生政策提供信息。