antigenicity
简明释义
英[ˌæn.tɪ.dʒəˈnɪs.ɪ.ti]美[ˌæn.tɪ.dʒəˈnɪs.ɪ.ti]
n. [免疫] 抗原性
英英释义
Antigenicity refers to the ability of a substance, typically a foreign protein or polysaccharide, to provoke an immune response in the body. | 抗原性指的是一种物质，通常是外源性蛋白质或多糖，诱发机体免疫反应的能力。 |
单词用法
同义词
| 免疫原性 | The immunogenicity of the vaccine is crucial for its effectiveness. | 疫苗的免疫原性对其有效性至关重要。 | |
| 反应性 | The reactivity of the antigen can vary based on the host's immune system. | 抗原的反应性可能因宿主的免疫系统而异。 |
反义词
| 耐受性 | Immune tolerance can prevent the body from attacking its own cells. | 免疫耐受可以防止身体攻击自身细胞。 | |
| 非免疫原性 | Non-immunogenicity is a desirable property for therapeutic proteins. | 非免疫原性是治疗性蛋白质的一个理想特性。 |
例句
1.The coating antigen in a 96 pore plate in the kit is the prokaryotic expression recombinant P30 protein, and has good antigenicity.
试剂盒中96孔板中的包被抗原为原核表达的重组P 30蛋白，其具有良好的抗原性。
2.The antigenicity of CD28 displayed on phage was detected by ELISA and FCM.
用ELISA和流式细胞仪检测展示在噬菌体上CD 28的抗原性。
3.As a new biomaterial scaffold, ADM has better tissue compatibility and lower antigenicity. It has been used in the field of periodontics.
作为一种新兴的皮肤黏膜移植材料，ADM拥有良好的组织相容性和极低的免疫性，现已被应用于牙周领域。
4.Although there is no significant change with thrombolytic activity of the mutant, antigenicity of the mutant decreases significantly.
该突变体的溶栓活性没有明显变化，而突变体的抗原性显著降低。
5.BACKGROUND Collagen type I possesses low antigenicity and provides special functions of scaffold structure for cell migration proliferation and secretion.
I型胶原抗原性低，具有为细胞移行、增殖和分泌提供支架结构的特殊功能。
6.In some cell lines there is a similar periodicity in changes of cell surface antigenicity or response to wheat germ agglutinin.
在某些细胞系中，细胞表面抗原性或对表胚凝集素的反应方面有相近似的周期性变化。
7.ANTHEPROT software predicted that it possessed good hydrophobicity and antigenicity.
ANTHEPROT软件预测其蛋白质具有良好的疏水性和抗原性。
8.The researchers tested the antigenicity of the modified virus in animal models.
研究人员在动物模型中测试了改造病毒的抗原性。
9.The antigenicity of the protein is crucial for its effectiveness as a therapeutic agent.
该蛋白的抗原性对其作为治疗剂的有效性至关重要。
10.Researchers found that the antigenicity of the virus was significantly altered over time.
研究人员发现，病毒的抗原性随着时间显著改变。
11.Understanding the antigenicity of allergens can help in developing better treatments for allergies.
了解过敏原的抗原性可以帮助开发更好的过敏治疗方法。
12.The study aimed to evaluate the antigenicity of the new vaccine in various populations.
该研究旨在评估新疫苗在不同人群中的抗原性。
作文
The concept of antigenicity refers to the ability of a substance, typically a foreign molecule, to provoke an immune response in the body. It plays a crucial role in immunology and is fundamental to our understanding of how the immune system identifies and reacts to pathogens. When we talk about antigenicity (抗原性), we are essentially discussing the properties that allow certain molecules, known as antigens, to be recognized by antibodies or T-cell receptors. This recognition is vital for the immune system to function effectively, as it enables the body to distinguish between self and non-self entities. In the field of vaccine development, the antigenicity (抗原性) of a vaccine is one of the most critical factors determining its effectiveness. A vaccine must contain antigens that are sufficiently recognizable by the immune system to elicit a strong and lasting response. For example, during the development of the COVID-19 vaccines, scientists focused on the spike protein of the SARS-CoV-2 virus because of its high antigenicity (抗原性). By introducing this specific antigen into the body, the vaccine trains the immune system to recognize and combat the actual virus if encountered in the future. However, not all antigens are created equal. The antigenicity (抗原性) of a substance can be influenced by various factors, including its structure, size, and the presence of specific epitopes—regions on the antigen that are recognized by immune cells. Larger and more complex molecules tend to exhibit higher antigenicity (抗原性) compared to smaller ones. Additionally, modifications to the antigen, such as glycosylation, can enhance or reduce its ability to provoke an immune response. Another important aspect of antigenicity (抗原性) is its relationship with immunological tolerance. The immune system must be able to tolerate self-antigens to prevent autoimmune diseases, where the body mistakenly attacks its own tissues. Understanding the balance between antigenicity (抗原性) and tolerance is essential for developing therapies for autoimmune conditions and for the safe application of immunotherapies. In clinical settings, measuring the antigenicity (抗原性) of a potential therapeutic agent is crucial. For instance, in cancer immunotherapy, identifying the antigenicity (抗原性) of tumor-associated antigens allows for the development of targeted treatments that can effectively stimulate the immune system to attack cancer cells. Furthermore, the study of antigenicity (抗原性) extends to the field of allergy research. Allergens are typically proteins that possess high antigenicity (抗原性) and can trigger inappropriate immune responses in sensitive individuals. Understanding the mechanisms behind antigenicity (抗原性) can lead to better management and treatment options for allergic reactions. In summary, antigenicity (抗原性) is a fundamental concept in immunology that influences vaccine development, cancer therapy, and allergy treatment. Its significance cannot be overstated, as it underpins the body's ability to recognize and respond to foreign substances. As research continues to evolve, a deeper understanding of antigenicity (抗原性) will undoubtedly lead to advancements in medical science and improved health outcomes for individuals worldwide.
