transannular interaction

简明释义

跨环相互酌

英英释义

例句

1.In organic chemistry, understanding the transannular interaction 跨环相互作用 can help predict reaction pathways.

在有机化学中，理解transannular interaction 跨环相互作用可以帮助预测反应路径。

2.The study focused on the transannular interaction 跨环相互作用 between the two molecular rings, revealing significant effects on stability.

这项研究集中在两个分子环之间的transannular interaction 跨环相互作用，揭示了对稳定性的重要影响。

3.Computational models often include transannular interaction 跨环相互作用 to enhance accuracy in predicting molecular behavior.

计算模型通常包括transannular interaction 跨环相互作用以提高预测分子行为的准确性。

4.The phenomenon of transannular interaction 跨环相互作用 is crucial in the design of new pharmaceuticals.

在新药设计中，transannular interaction 跨环相互作用现象至关重要。

5.The researchers observed a strong transannular interaction 跨环相互作用 that influenced the compound's reactivity.

研究人员观察到一种强烈的transannular interaction 跨环相互作用，影响了化合物的反应性。

作文

In the realm of chemistry and molecular interactions, understanding the various forces that govern the behavior of molecules is crucial. One such phenomenon that has garnered attention in recent years is the concept of transannular interaction. This term refers to the interactions that occur across a ring structure in a molecule, particularly in cyclic compounds. These interactions can significantly influence the stability, reactivity, and overall properties of the molecule. To grasp the significance of transannular interaction, it is essential to explore its implications in various chemical contexts.Cyclic compounds, such as cyclohexane or more complex bicyclic structures, often exhibit unique properties due to their ring formations. The presence of a ring can restrict the conformational flexibility of the molecule, leading to specific spatial arrangements of atoms. Within these rings, atoms may interact with each other in ways that are not possible in acyclic compounds. This is where transannular interaction comes into play. It involves the non-bonding interactions between atoms that are not directly adjacent but are separated by the ring structure. For instance, in certain bicyclic systems, a hydrogen atom on one side of the ring can interact with another atom, such as a nitrogen or oxygen, located on the opposite side of the ring.The significance of transannular interaction can be observed in the field of organic synthesis. Chemists often leverage these interactions to stabilize intermediates during reactions or to guide the formation of specific products. For example, when synthesizing complex natural products, understanding how transannular interaction influences the geometry of the reacting species can lead to higher yields and selectivity. Furthermore, these interactions can also play a role in determining the stereochemistry of a reaction, which is vital for the biological activity of many pharmaceutical compounds.Moreover, transannular interaction is not just limited to organic chemistry; it also finds relevance in biochemistry. Many biological molecules, such as enzymes and nucleic acids, have intricate ring structures that facilitate crucial interactions. The dynamics of these interactions can affect enzyme catalysis and the stability of DNA and RNA structures. For instance, in ribonucleic acid (RNA), the folding and functionality are often influenced by transannular interaction among various nucleotide bases, which can lead to the formation of secondary structures essential for biological processes.In conclusion, transannular interaction is a fundamental concept that highlights the importance of molecular geometry and spatial arrangements in determining the behavior of cyclic compounds. Its implications extend across various fields, from organic synthesis to biochemistry, underscoring the interconnectedness of molecular interactions. As research continues to delve deeper into the complexities of molecular behavior, understanding transannular interaction will undoubtedly remain a key area of focus for chemists and biochemists alike. This knowledge not only enhances our comprehension of chemical principles but also paves the way for innovative applications in drug design and molecular engineering.

在化学和分子相互作用领域，理解支配分子行为的各种力量至关重要。近年来，transannular interaction（跨环相互作用）这一概念引起了人们的关注。这个术语指的是发生在分子环结构之间的相互作用，特别是在环状化合物中。这些相互作用可以显著影响分子的稳定性、反应性和整体性质。要理解transannular interaction的重要性，有必要探讨其在各种化学背景下的影响。环状化合物，如环己烷或更复杂的双环结构，通常由于其环形结构而表现出独特的性质。环的存在可能限制分子的构象灵活性，从而导致原子的特定空间排列。在这些环内，原子之间可能以在非环状化合物中无法实现的方式进行相互作用。这就是transannular interaction发挥作用的地方。它涉及到不直接相邻但被环结构分隔的原子之间的非键合相互作用。例如，在某些双环系统中，环一侧的氢原子可以与位于环另一侧的另一个原子（如氮或氧）相互作用。transannular interaction的重要性可以在有机合成领域中观察到。化学家通常利用这些相互作用来稳定反应过程中的中间体或引导特定产物的形成。例如，在合成复杂天然产物时，了解transannular interaction如何影响反应物的几何形状可以提高产率和选择性。此外，这些相互作用还可以在确定反应的立体化学方面发挥作用，这对于许多药物化合物的生物活性至关重要。此外，transannular interaction不仅限于有机化学；它在生物化学中也具有相关性。许多生物分子，如酶和核酸，具有复杂的环结构，促进关键的相互作用。这些相互作用的动态变化可以影响酶催化和DNA、RNA结构的稳定性。例如，在核糖核酸（RNA）中，不同核苷酸碱基之间的transannular interaction会影响其折叠和功能，这对于生物过程至关重要。总之，transannular interaction是一个基本概念，强调了分子几何形状和空间排列在决定环状化合物行为中的重要性。它的影响扩展到各个领域，从有机合成到生物化学，突显了分子相互作用的相互关联性。随着研究不断深入分子行为的复杂性，理解transannular interaction无疑将继续成为化学家和生物化学家关注的重点领域。这一知识不仅增强了我们对化学原理的理解，也为药物设计和分子工程中的创新应用铺平了道路。