thiamine diphosphate

简明释义

二磷酸硫胺

英英释义

例句

1.In the metabolic pathway, thiamine diphosphate (硫胺素二磷酸) plays a critical role in carbohydrate metabolism.

在代谢途径中，thiamine diphosphate（硫胺素二磷酸）在碳水化合物代谢中发挥着关键作用。

2.The enzyme pyruvate dehydrogenase requires thiamine diphosphate (硫胺素二磷酸) as a cofactor to convert pyruvate into acetyl-CoA.

酶丙酮酸脱氢酶需要thiamine diphosphate（硫胺素二磷酸）作为辅因子，将丙酮酸转化为乙酰辅酶A。

3.Deficiency in thiamine diphosphate (硫胺素二磷酸) can lead to neurological disorders.

缺乏thiamine diphosphate（硫胺素二磷酸）可能导致神经系统疾病。

4.Research shows that thiamine diphosphate (硫胺素二磷酸) supplementation may improve cognitive function.

研究表明，补充thiamine diphosphate（硫胺素二磷酸）可能改善认知功能。

5.Food sources rich in thiamine can help maintain adequate levels of thiamine diphosphate (硫胺素二磷酸) in the body.

富含硫胺素的食物可以帮助维持体内适量的thiamine diphosphate（硫胺素二磷酸）。

作文

Thiamine diphosphate, often abbreviated as TDP, is a crucial coenzyme in the metabolism of carbohydrates and amino acids. It is the active form of vitamin B1, also known as thiamine. This compound plays an essential role in cellular processes, particularly in the conversion of pyruvate to acetyl-CoA, which is a significant step in the Krebs cycle. The importance of thiamine diphosphate (硫胺素二磷酸) cannot be overstated, as it is vital for energy production in the body.The human body requires a constant supply of thiamine through diet, as it cannot synthesize this vitamin on its own. Foods rich in thiamine include whole grains, legumes, nuts, and seeds. When we consume these foods, thiamine is absorbed in the intestines and converted into its active form, thiamine diphosphate (硫胺素二磷酸), within the cells. This conversion is critical because only in this form can thiamine participate in various enzymatic reactions that facilitate energy metabolism.One of the key functions of thiamine diphosphate (硫胺素二磷酸) is its involvement in the decarboxylation of alpha-keto acids, such as pyruvate and alpha-ketoglutarate. This process is essential for the generation of energy in the form of ATP (adenosine triphosphate), which fuels cellular activities. Additionally, thiamine diphosphate (硫胺素二磷酸) assists in the synthesis of neurotransmitters, which are crucial for proper brain function and communication between nerve cells.Deficiency in thiamine can lead to serious health issues. One of the most well-known conditions associated with thiamine deficiency is beriberi, which affects the cardiovascular and nervous systems. Symptoms of beriberi can include weakness, nerve damage, and heart problems. Another condition related to thiamine deficiency is Wernicke-Korsakoff syndrome, often seen in individuals with chronic alcoholism. This syndrome is characterized by severe neurological symptoms, including confusion, memory loss, and coordination problems.To prevent thiamine deficiency, it is essential to maintain a balanced diet that includes sufficient amounts of foods rich in this vitamin. In certain populations, such as those with malabsorption issues or increased metabolic demands, supplementation may be necessary to ensure adequate levels of thiamine diphosphate (硫胺素二磷酸) in the body.In conclusion, thiamine diphosphate (硫胺素二磷酸) is a vital coenzyme that plays a significant role in energy metabolism and overall health. Understanding its functions and the consequences of its deficiency can help individuals make informed dietary choices and promote better health outcomes. As research continues to explore the various roles of thiamine and its active form, thiamine diphosphate (硫胺素二磷酸), we gain deeper insights into how essential vitamins contribute to our well-being and vitality.

硫胺素二磷酸，通常缩写为TDP，是碳水化合物和氨基酸代谢中的关键辅酶。它是维生素B1的活性形式，也称为硫胺素。该化合物在细胞过程中发挥着重要作用，特别是在丙酮酸转化为乙酰辅酶A的过程中，这是克雷布斯循环中的一个重要步骤。硫胺素二磷酸的重要性不容小觑，因为它对身体的能量生产至关重要。人体需要通过饮食不断补充硫胺素，因为它无法自行合成这种维生素。富含硫胺素的食物包括全谷物、豆类、坚果和种子。当我们摄入这些食物时，硫胺素在肠道中被吸收，并在细胞内转化为其活性形式硫胺素二磷酸。这一转化至关重要，因为只有在这种形式下，硫胺素才能参与各种酶促反应，促进能量代谢。硫胺素二磷酸的一个关键功能是参与α-酮酸的脱羧反应，如丙酮酸和α-酮戊二酸。这个过程对于以ATP（腺苷三磷酸）的形式生成能量至关重要，ATP为细胞活动提供动力。此外，硫胺素二磷酸还协助合成神经递质，这对大脑功能和神经细胞之间的沟通至关重要。硫胺素缺乏会导致严重的健康问题。与硫胺素缺乏相关的最著名的疾病之一是脚气病，它影响心血管和神经系统。脚气病的症状包括虚弱、神经损伤和心脏问题。与硫胺素缺乏相关的另一种疾病是威尔尼克-科尔萨科夫综合症，常见于慢性酗酒者。这种综合症的特征是严重的神经症状，包括混乱、记忆丧失和协调问题。为了防止硫胺素缺乏，保持均衡饮食，确保摄入足够的富含这种维生素的食物至关重要。在某些人群中，例如那些有吸收问题或代谢需求增加的人，可能需要补充，以确保体内有足够的硫胺素二磷酸。总之，硫胺素二磷酸是一个重要的辅酶，在能量代谢和整体健康中发挥着重要作用。了解其功能及缺乏的后果可以帮助人们做出明智的饮食选择，促进更好的健康结果。随着研究持续探索硫胺素及其活性形式硫胺素二磷酸的各种角色，我们对必需维生素如何促进我们的健康和活力有了更深入的认识。